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From Mice to Men: TRPC3 in Cerebellar Ataxia

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Abstract

The dominantly inherited cerebellar ataxias are a clinically and genetically heterogeneous group of neurodegenerative disorders. Studies using mouse models as well as recent genetic and transcriptomic human findings point to an important role for TRPC3 signaling in cerebellar ataxia.

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The author declares no conflict of interest.

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Authors and Affiliations

  1. Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Sherrington Road, Oxford, OX1 3PT, UK

    Esther B. E. Becker

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  1. Esther B. E. Becker
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Correspondence to Esther B. E. Becker.

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Becker, E.B.E. From Mice to Men: TRPC3 in Cerebellar Ataxia. Cerebellum 16, 877–879 (2017). https://doi.org/10.1007/s12311-015-0663-y

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  • DOI: https://doi.org/10.1007/s12311-015-0663-y

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