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Assessment of Hematological Parameters in Pulmonary Tuberculosis Patients

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Abstract

The aim of the study was the assessment of hematological parameters in pulmonary tuberculosis patients. Forty patients diagnosed with tuberculosis were recruited from the Institute of Thoracic Medicine on the basis of history, clinical examination, chest radiography, sputum examination and related laboratory parameters and were compared with age and sex matched healthy volunteers (n = 40). Hematological parameters and CRP in tuberculosis patients were determined. The mean values for serum hemoglobin level, RBC count and platelet count in PTB was found to be less (p < 0.001). Erythrocyte sedimentation rate (ESR), plasma C-reactive protein, WBC count in PTB subjects was increased (p < 0.001 for ESR & CRP, p < 0.05 for WBCs) and all were statistically significant. This study demonstrated that serum hemoglobin level, RBC count and platelet count was decreased in tuberculosis patients whereas ESR, CRP and WBC count was increased when compared with healthy controls.

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Authors and Affiliations

  1. Unit of Biochemistry, Faculty of Medicine, AIMST University, Bedong, Kedah, Malaysia

    K. Rohini

  2. Professor in Biochemistry, Xavier University School of Medicine, Oranjestad, Aurba

    M. Surekha Bhat

  3. Unit of Psychiatry, Faculty of Medicine, AIMST University, Bedong, Kedah, Malaysia

    P. S. Srikumar

  4. Pulmonologist, Eswar Medical Foundation, Chennai, India

    A. Mahesh Kumar

Authors
  1. K. Rohini
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  2. M. Surekha Bhat
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  3. P. S. Srikumar
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  4. A. Mahesh Kumar
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Correspondence to K. Rohini.

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There were no conflicts of interest regarding the publication of this article.

Ethical Standards

The study protocol was approved by the Institutional ethics committee and was carried out in accordance with the principle of Declaration of Helsinki.

Informed Consent

Informed consent was obtained from all the subjects.

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Rohini, K., Surekha Bhat, M., Srikumar, P.S. et al. Assessment of Hematological Parameters in Pulmonary Tuberculosis Patients. Ind J Clin Biochem 31, 332–335 (2016). https://doi.org/10.1007/s12291-015-0535-8

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  • DOI: https://doi.org/10.1007/s12291-015-0535-8

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