Abstract
Hematopoietic stem cell transplantation is curative therapy in benign and malignant diseases. Adequate stem cell dose is one of the most important marker of engraftment. Several methods have been developed to enumerate CD34+ cells. We present our data on 147 samples analysis. There was a clear linear correlation between two methods. Both methods were effective. Both single vs dual platform analysis yield similar results. Single platform analysis is easier to perform. In terms of cost reduction dual platform analysis is better.
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We acknowledge the help of Ms. Kavita from CMC Vellore for statistical analysis.
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Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
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Naithani, R., Dayal, N. & Dixit, G. Single Versus Dual Platform Analysis for Hematopoietic Stem Cell Enumeration Using ISHAGE Protocol. Indian J Hematol Blood Transfus 33, 370–374 (2017). https://doi.org/10.1007/s12288-016-0749-9
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DOI: https://doi.org/10.1007/s12288-016-0749-9