Original Article

Indian Journal of Hematology and Blood Transfusion

, Volume 28, Issue 2, pp 77-81

First online:

Prevalence and Characterization of Thrombocytopenia in Pregnancy in Indian Women

  • Singh NishaAffiliated withDepartment of Obstetrics & Gynecology, CSM Medical University Email author 
  • , Dhakad AmitaAffiliated withDepartment of Obstetrics & Gynecology, CSM Medical University
  • , Singh UmaAffiliated withDepartment of Obstetrics & Gynecology, CSM Medical University
  • , A. K. TripathiAffiliated withDepartment of Medicine, CSM Medical University
  • , Sankhwar PushplataAffiliated withDepartment of Obstetrics & Gynecology, CSM Medical University

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To find the prevalence and causes of thrombocytopenia during pregnancy. An analytical prospective observational study was conducted in Department of Obstetrics & Gynecology, CSMMU, Lucknow. 1079 antenatal women screened for thrombocytopenia and investigated for cause and management strategies and fetomaternal outcome were recorded. Prevalence of thrombocytopenia was 8.8%. Gestational thrombocytopenia was seen in 64.2%, obstetric in 22.1% and medical in 13.68% cases. Mean platelet count in controls was lower with a significant fall (P < 0.001) in the platelet count as pregnancy advanced. Hypertensive and hepatic disorders were the most common obstetric causes of thrombocytopenia. Mode of delivery was not affected by thrombocytopenia. Maternal morbidity and mortality was seen only in medical and obstetric thrombocytopenia. The low platelet counts and declining trend with increasing gestational age predispose Indian women to risk of thrombocytopenia and a routine platelet count is suggested.


Platelet count Gestational thrombocytopenia Obstetric thrombocytopenia DIC Medical thrombocytopenia Pregnancy with ITP