, Volume 16, Issue 4, pp 243-247
Date: 23 May 2009

Breast cancer risk assessment for possible tailored screening for Japanese women

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Abstract

Accurate risk assessment for individual women is essential for effective screening of breast cancer (BC) in Japan, because the incidence of BC is still lower than in Western countries. We investigated various new risk factors of BC by means of case control studies and found that serum estrone and adiponectine levels as well as mammographic breast density were significantly correlated to BC risk. Combining these new factors and conventional risk factors of BC may result in a new and useful risk assessment tool, may improve the cost-effectiveness of screening, and may enable us to reduce the BC mortality of Japanese women.

This article is based on a presentation delivered at the Presidential Symposium, “From standardization to personalization in breast cancer treatment,” held on 26 September 2008 at the 16th Annual Meeting of the Japanese Breast Cancer Society in Osaka.