Conference Paper Presidential Symposium: From standardization to personalization in breast cancer treatment

Breast Cancer

, Volume 16, Issue 4, pp 243-247

Breast cancer risk assessment for possible tailored screening for Japanese women

  • Yasuhiro TamakiAffiliated withDepartment of Breast and Endocrine Surgery, Osaka University Graduate School of Medicine
  • , Yasuyuki KotsumaAffiliated withDepartment of Breast and Endocrine Surgery, Osaka University Graduate School of Medicine
  • , Yasuo MiyoshiAffiliated withDepartment of Breast and Endocrine Surgery, Hyogo College of Medicine
  • , Shinzaburo NoguchiAffiliated withDepartment of Breast and Endocrine Surgery, Osaka University Graduate School of Medicine Email author 

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Abstract

Accurate risk assessment for individual women is essential for effective screening of breast cancer (BC) in Japan, because the incidence of BC is still lower than in Western countries. We investigated various new risk factors of BC by means of case control studies and found that serum estrone and adiponectine levels as well as mammographic breast density were significantly correlated to BC risk. Combining these new factors and conventional risk factors of BC may result in a new and useful risk assessment tool, may improve the cost-effectiveness of screening, and may enable us to reduce the BC mortality of Japanese women.

Keywords

Breast cancer screening Risk factor