Research Article

Nano Research

, Volume 3, Issue 7, pp 481-489

Open Access This content is freely available online to anyone, anywhere at any time.

Biosynthesis of biocompatible cadmium telluride quantum dots using yeast cells

  • Haifeng BaoAffiliated withDepartment of Chemical Engineering, Monash University
  • , Na HaoAffiliated withDepartment of Chemical Engineering, Monash University
  • , Yunxia YangAffiliated withDepartment of Chemical Engineering, Monash University
  • , Dongyuan ZhaoAffiliated withDepartment of Chemical Engineering, Monash University Email author 

Abstract

We demonstrate a simple and efficient biosynthesis method to prepare easily harvested biocompatible cadmium telluride (CdTe) quantum dots (QDs) with tunable fluorescence emission using yeast cells. Ultraviolet-visible (UV-vis) spectroscopy, photoluminescence (PL) spectroscopy, X-ray diffraction (XRD), and transmission electron microscopy (TEM) confirm that the CdTe QDs are formed via an extracellular growth and subsequent endocytosis pathway and have size-tunable optical properties with fluorescence emission from 490 to 560 nm and a cubic zinc blende structure with good crystallinity. In particular, the CdTe QDs with uniform size (2-3.6 nm) are protein-capped, which makes them highly soluble in water, and in situ bio-imaging in yeast cells indicates that the biosynthesized QDs have good biocompatibility. This work provides an economic and environmentally friendly approach to synthesize highly fluorescent biocompatible CdTe QDs for bio-imaging and bio-labeling applications.
http://static-content.springer.com/image/art%3A10.1007%2Fs12274-010-0008-6/MediaObjects/12274_2010_8_Fig1_HTML.jpg

Keywords

Cadmium telluride (CdTe) quantum dots biosynthesis biocompatible in situ bio-imaging