Research Article

Nano Research

, Volume 2, Issue 12, pp 938-944

Open Access This content is freely available online to anyone, anywhere at any time.

Nanopumping molecules via a carbon nanotube

  • Min ChenAffiliated withDepartment of Materials Science and Engineering, Sichuan UniversityDepartment of Optoelectronic Technology, Chengdu University of Information TechnologyDepartment of Materials Science and Engineering, University of Utah
  • , Ji ZangAffiliated withDepartment of Materials Science and Engineering, University of Utah
  • , Dingquan XiaoAffiliated withDepartment of Materials Science and Engineering, Sichuan University
  • , C. ZhangAffiliated withSchool of Engineering Physics, University of Wollongong
  • , Feng LiuAffiliated withDepartment of Materials Science and Engineering, University of Utah Email author 

Abstract

We demonstrate the feasibility of using a carbon nanotube to nanopump molecules. Molecular dynamics simulations show that the transport and ejection of a C20 molecule via a single-walled carbon nanotube (SWNT) can be achieved by a sustained mechanical actuation driven by two oscillating tips. The optimal condition for nanopumping is found when the tip oscillation frequency and magnitude correlate to form quasi steady-state mechanical wave propagation in the SWNT, so that the energy transfer process is optimal leading to maximal molecular translational motion and minimal rotational motion. Our finding provides a potentially useful mechanism for using an SWNT as a vehicle to deliver large drug molecules.
http://static-content.springer.com/image/art%3A10.1007%2Fs12274-009-9096-6/MediaObjects/12274_2009_9096_Fig1_HTML.jpg

Keywords

Carbon nanotube nanopumping drug delivery MD simualtion