Capacitively coupled shortwave radiofrequency fields (13.56 MHz) resistively heat low concentrations (∼1 ppm) of gold nanoparticles with a thermal power dissipation of ∼380 kW/g of gold. Smaller diameter gold nanoparticles (< 50 nm) heat at nearly twice the rate of larger diameter gold nanoparticles (≥50 nm), which is attributed to the higher resistivity of smaller gold nanostructures. A Joule heating model has been developed to explain this phenomenon and provides critical insights into the rational design and engineering of nanoscale materials for noninvasive thermal therapy of cancer.



Resistivity radiofrequency gold nanoparticles cancer thermal

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© Tsinghua University Press and Springer-Verlag Berlin Heidelberg 2009