Research Article

Nano Research

, Volume 2, Issue 5, pp 400-405

Open Access This content is freely available online to anyone, anywhere at any time.

Size-dependent joule heating of gold nanoparticles using capacitively coupled radiofrequency fields

  • Christine H. MoranAffiliated withDepartment of Bioengineering, Rice UniversityDepartment of Surgical Oncology, MD Anderson Cancer Center
  • , Sean M. WainerdiAffiliated withDepartment of Surgical Oncology, MD Anderson Cancer CenterDepartment of Bioengineering, Texas A&M University
  • , Tonya K. CherukuriAffiliated withDepartment of Chemistry and Richard E. Smalley Institute for Nanoscale Science and Technology, Rice University
  • , Carter KittrellAffiliated withDepartment of Chemistry and Richard E. Smalley Institute for Nanoscale Science and Technology, Rice University
  • , Benjamin J. WileyAffiliated withDepartment of Chemistry and Chemical Biology, Harvard University
  • , Nolan W. NicholasAffiliated withDepartment of Physics and Richard E. Smalley Institute for Nanoscale Science and Technology, Rice University
  • , Steven A. CurleyAffiliated withDepartment of Surgical Oncology, MD Anderson Cancer CenterDepartment of Mechanical Engineering and Material Science, Rice University
  • , John S. Kanzius
  • , Paul CherukuriAffiliated withDepartment of Surgical Oncology, MD Anderson Cancer CenterDepartment of Chemistry and Richard E. Smalley Institute for Nanoscale Science and Technology, Rice UniversityDepartment of Chemistry and Chemical Biology, Harvard UniversityDepartment of Experimental Therapeutics, MD Anderson Cancer Center Email author 

Abstract

Capacitively coupled shortwave radiofrequency fields (13.56 MHz) resistively heat low concentrations (∼1 ppm) of gold nanoparticles with a thermal power dissipation of ∼380 kW/g of gold. Smaller diameter gold nanoparticles (< 50 nm) heat at nearly twice the rate of larger diameter gold nanoparticles (≥50 nm), which is attributed to the higher resistivity of smaller gold nanostructures. A Joule heating model has been developed to explain this phenomenon and provides critical insights into the rational design and engineering of nanoscale materials for noninvasive thermal therapy of cancer.

http://static-content.springer.com/image/art%3A10.1007%2Fs12274-009-9048-1/MediaObjects/12274_2009_9048_Fig1_HTML.jpg

Keywords

Resistivity radiofrequency gold nanoparticles cancer thermal