Archives of Pharmacal Research

, Volume 37, Issue 1, pp 43-52

First online:

Carbon-based drug delivery carriers for cancer therapy

  • Dong-Jin LimAffiliated withDepartment of Biomedical Engineering, University of Alabama at Birmingham
  • , Myeongbu SimAffiliated withSchool of Integrative Engineering, Chung-Ang University
  • , Leeseul OhAffiliated withSchool of Chemical Engineering, Chung-Ang University
  • , Kyunghee LimAffiliated withSchool of Chemical Engineering, Chung-Ang University
  • , Hansoo ParkAffiliated withSchool of Integrative Engineering, Chung-Ang University Email author 

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In the search to improve anticancer therapies, several drug carriers, including carbon-based nanomaterials have been studied. Both liposomes and polymeric microspheres have been used in anticancer drugs. However, there remains an on-going need for better therapeutic materials that have good drug solubility, an ability to reduce systemic toxicity through specific-tumor targeting, and rapid clearance. In this regard, carbon allotropes such as graphene oxide (GOs), carbon nanotubes (CNTs), and nanodiamonds (NDs), have been investigated, as they possess sufficient surface-to-volume ratio, thermal conductivity, rigid structural properties capable of post-chemical modification, and excellent biocompatibility. This review is aimed at exploring these carbon-based nanomaterials for use as multifaceted cancer drug carriers and is intended to demonstrate that GOs, CNTs, and NDs are likely to improve chemotherapeutical strategy for cancers in either a sole or combinational manner.


Nanodiamonds Graphene oxide Carbon nanotube Drug delivery