3D-Migrationsassays im Hochdurchsatz
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- Larson, B., Rieger, L., Tseng, H. et al. Biospektrum (2016) 22: 395. doi:10.1007/s12268-016-0704-1
Migration assays are a common tool to screen toxic effects of compounds. However, assays using monolayer cell cultures may not entirely represent a native in vivo environment and may result in misinterpretation of compound toxicity. Magnetic 3D bioprinting in combination with automated kinetic imaging provides an easy and robust high-throughput screening approach of compound effects on cell migration in a 3D environment.