BIOspektrum

, Volume 22, Issue 4, pp 395–397

3D-Migrationsassays im Hochdurchsatz

  • Brad Larson
  • Leonie Rieger
  • Hubert Tseng
  • Glauco R. Souza
  • Aleksandra Velkova-Krei
3D-Zellkultur

DOI: 10.1007/s12268-016-0704-1

Cite this article as:
Larson, B., Rieger, L., Tseng, H. et al. Biospektrum (2016) 22: 395. doi:10.1007/s12268-016-0704-1

Abstract

Migration assays are a common tool to screen toxic effects of compounds. However, assays using monolayer cell cultures may not entirely represent a native in vivo environment and may result in misinterpretation of compound toxicity. Magnetic 3D bioprinting in combination with automated kinetic imaging provides an easy and robust high-throughput screening approach of compound effects on cell migration in a 3D environment.

Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Brad Larson
    • 1
  • Leonie Rieger
    • 1
  • Hubert Tseng
    • 2
  • Glauco R. Souza
    • 2
  • Aleksandra Velkova-Krei
    • 3
  1. 1.Biotek InstrumentsWinooskiUSA
  2. 2.Nano3D BiosciencesHoustonUSA
  3. 3.Greiner Bio-One GmbHFrickenhausenGermany

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