Abstract
Most bacteria are able to grow in biofilms in which they effectively resist antimicrobial agents. This leads to a general problem, since traditional treatments of bacteria and prevention strategies become mostly ineffective. Novel strategies for biofilm inhibition are thus urgently required. Compounds interfering with cell-cell communication (quorum sensing) crucial for biofilm formation are promising targets for alternative strategies. Here, we report on a recently established assay enabling identification of quorum quenching compounds from environmental samples.
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Nancy Weiland-Bräuer 2000–2006 Biologiestudium (Diplom), Universität zu Kiel. 2006–2010 Promotion am Institut für Allgemeine Mikrobiologie (IFAM), Universität zu Kiel, dort 2010–2012 Postdoktorandin. 2012–2014 Elternzeit. 2014 Beginn der Habilitation am IFAM.
Ruth A. Schmitz-Streit 1984–1989 Biologiestudium (Diplom), Universität Marburg; 1990–1992 Promotion. 1993 Postdoktorandin in Marburg und 1994–1996 an der University of California, Berkeley, CA, USA. 1996–2001 Habilitation am Institut für Mikrobiologie und Genetik, Universität Göttingen. 2001–2004 Gruppenleiterin an der Universität Göttingen (Heisenberg-Stipendiatin). Seit 2004 Lehrstuhlinhaberin und Direktorin am Institut für Allgemeine Mikrobiologie (IFAM), Universität zu Kiel.
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Weiland-Bräuer, N., Schmitz-Streit, R.A. Quorum quenching–Stören friede zwischenbakterieller Beziehungen. Biospektrum 22, 362–364 (2016). https://doi.org/10.1007/s12268-016-0698-8
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DOI: https://doi.org/10.1007/s12268-016-0698-8