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Lichtregulierte Genexpression

Optogenetik und Biotechnologie

  • Wissenschaft · Methoden
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Abstract

Sensory photoreceptors mediate vital organismal adaptations in response to light. Certain photoreceptors afford control by light over gene expression with minimal invasiveness, full reversibility, and high spatiotemporal resolution. The ability to precisely regulate in space and time the formation of arbitrary gene products now enables applications in optogenetics and biotechnology in both prokaryotic and eukaryotic hosts.

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Authors and Affiliations

  1. Institut für Biologie, HU Berlin, Berlin, Germany

    Ralph P. Diensthuber, Robert Ohlendorf, Tobias Gleichmann, Roman Schubert & Andreas Möglich

  2. Institut für Biologie, Biophysikalische Chemie, Humboldt-Universität zu Berlin, Invalidenstraße 42, D-10115, Berlin, Germany

    Andreas Möglich

Authors
  1. Ralph P. Diensthuber
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  2. Robert Ohlendorf
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  3. Tobias Gleichmann
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  4. Roman Schubert
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  5. Andreas Möglich
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Corresponding author

Correspondence to Andreas Möglich.

Additional information

Robert Ohlendorf 2006–2009 Biologiestudium an der Universität Osnabrück. 2009–2011 Biophysikstudium an der Humboldt-Universität Berlin, dort seit 2011 Promotion in der Arbeitsgruppe Biophysikalische Chemie.

Roman Schubert 2003–2010 Biotechnologiestudium an der Universität Braunschweig. Seit 2010 Promotion in der Arbeitsgruppe Biophysikalische Chemie, HU Berlin.

Ralph P. Diensthuber 2000–2005 Biochemiestudium an der Universität Hannover. 2005–2009 Promotion an der Medizinischen Hochschule Hannover (MHH) in der Arbeitsgruppe von Prof. Dr. G. Tsiavaliaris. 2009–2011 Postdoc an der MHH in der Arbeitsgruppe von Prof. Dr. D. J. Manstein. Seit 2011 Postdoc in der Arbeitsgruppe Biophysikalische Chemie, HU Berlin.

Tobias Gleichmann 2007–2012 Biotechnologiestudium an der TU Berlin.

Andreas Möglich 1996–2001 Biochemiestudium an der Universität Regensburg. 2002–2005 Promotion am Biozentrum Basel, Schweiz, in der Arbeitsgruppe von Prof. Dr. T. Kiefhaber. 2006–2010 Postdoc an der University of Chicago, Illinois, USA, in der Arbeitsgruppe von Prof. Dr. K. Moffat. Seit 2010 Professor für Biophysikalische Chemie an der HU Berlin.

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Diensthuber, R.P., Ohlendorf, R., Gleichmann, T. et al. Lichtregulierte Genexpression. Biospektrum 19, 149–151 (2013). https://doi.org/10.1007/s12268-013-0286-0

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  • DOI: https://doi.org/10.1007/s12268-013-0286-0

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