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Ishigoside, a new glyceroglycolipid isolated from the brown alga Ishige okamurae

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Abstract

A new glyceroglycolipid, ishigoside (1, 2-di-O-palmitoyl-3-O-(6-deoxy-6-amino)-α-D-glucopyranosyl-glycerol, 1), along with two known compounds were isolated from the brown alga Ishige okamurae. The structure of the new compound was determined on the basis of spectroscopic analysis, including 1D and 2D NMR, MS techniques and chemical methods. Moreover, direct free radical scavenging activities of ishigoside were investigated by electron spin resonance spectrometry (ESR) technique. The results suggested that ishigoside was a potential free-radical scavenger against DPPH, hydroxyl, alkyl, and superoxide radicals with the EC50 of 31.2, 16.7, 22.7, and 26.8 μM, respectively.

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Authors and Affiliations

  1. Marine Bioprocess Research Center, Pukyong National University, Busan, 608-737, Korea

    Yanping Zou, Yong Li & Se-Kwon Kim

  2. Resource Institute, Academy of Sciences of Traditional Chinese Medicine of Jilin Province, Changchun, 130021, China

    Yong Li

  3. Department of Chemistry, Dong-Eui University, Busan, 614-714, Korea

    Moon-Moo Kim

  4. Department of Chemistry, Pukyong National University, Busan, 608-737, Korea

    Sang-Hoon Lee & Se-Kwon Kim

Authors
  1. Yanping Zou
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  2. Yong Li
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  3. Moon-Moo Kim
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  4. Sang-Hoon Lee
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  5. Se-Kwon Kim
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Correspondence to Se-Kwon Kim.

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Zou, Y., Li, Y., Kim, MM. et al. Ishigoside, a new glyceroglycolipid isolated from the brown alga Ishige okamurae . Biotechnol Bioproc E 14, 20–26 (2009). https://doi.org/10.1007/s12257-008-0131-3

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  • DOI: https://doi.org/10.1007/s12257-008-0131-3

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