Skip to main content
SpringerLink
Log in

Orbito-maxillofacial mesenchymal chondrosarcoma with intracranial invasion and lung metastasis

Case report and review of the literature

  • case report
  • Published:
memo - Magazine of European Medical Oncology Aims and scope Submit manuscript

Summary

We report on a patient who presented with swelling to the left side of the face accompanied by exophthalmos. Imaging studies revealed a large expansive heterogeneous mass encroaching on the sinonasal region. Following intravenous contrast administration revealed a lesion with moderate enhancement and involvement of the ipsilateral orbital cavity with intracranial invasion. The patient underwent tumor resection and a biopsy confirmed the presence of a mesenchymal chondrosarcoma. Additional treatment included radiation therapy and the patient is currently receiving palliative and supportive care for advanced metastatic lung disease.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Sturgis EM, Potter BO. Sarcomas of the head and neck region. Curr Opin Oncol. 2003;15:239–52.

    Article  PubMed  Google Scholar 

  2. Quevedo FC, Batocchio Quevedo F, Barauna Neto JC, et al. Case report: chondrosarcoma of the head and neck. Hum Pathol. 2015; doi:10.1016/j.ehpc.2015.07.002.

    Google Scholar 

  3. Mahajan AM, Ganvir SM, Hazarey VK, Mahajan MC. Chondrosarcoma of the maxilla: a case report and review of literature. J Oral Maxillofac Pathol. 2013;17:269–73.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Halefoglu AM. Magnetic resonance imaging of neck chondrosarcoma: a case report. CMIG Extra Cases. 2005;29:23–6.

    Article  Google Scholar 

  5. Takahama A Jr, de Abreu Alves F, Prado FO, et al. Chondrosarcoma of the maxilla: report of two cases with different behaviours. J Craniomaxillofac Surg. 2012;40:71–4.

    Article  Google Scholar 

  6. Pontes HAR, Pontes FSC, de Abreu MC, et al. Clinicopathological analysis of head and neck chondrosarcoma: three case reports and literature review. Int J Oral Maxillofac Surg. 2012;41:203–10.

    Article  CAS  PubMed  Google Scholar 

  7. Gawande M, Swastika N, Chaudhary M, Patil S. Chondrosarcoma of maxilla. J Oral Maxillofac Pathol. 2014;18:423–7.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Evans HL, Ayala A, Romsdahl NM. Prognostic factors in chondrosarcoma of bone. A clinicopathologic analysis with emphasis on histologic grading. Cancer. 1977;40:818.

    Article  CAS  PubMed  Google Scholar 

  9. Van Damme JP, Schmitz S, Machiels JP, et al. Prognostic factors and assessment of staging systems for head and neck soft tissue sarcomas in adults. Eur J Surg Oncol. 2010;36:684–90.

    Article  PubMed  Google Scholar 

  10. Abdel-Fattah HM, et al. Hyoid bone chondrosarcoma with cervical nodal metastasis: a case report. Alex J Med. 2015;52(3):295–8. doi:10.1016/j.ajme.2015.10.002.

    Article  Google Scholar 

  11. Yang BT, Wang YZ, Wang XY, Wang ZC. Mesenchymal chondrosarcoma of the orbit: CT and MRI Findings. Clin Radiol. 2012;67:346–51.

    Article  CAS  PubMed  Google Scholar 

  12. Zagers GK, Ballo MT, Pisters PWT, et al. Prognostic factors for patients with localized soft-tissue sarcoma treated with conservation surgery and radiation therapy. Cancer. 2003;97:2530–43.

    Article  Google Scholar 

  13. Simsek B, Koybasioglu A, Yucel E, Gunhan O. Chondrosarcoma of the parapharyngeal space. Int J Oral Maxillofac Surg. 2005;34:803–5.

    Article  CAS  PubMed  Google Scholar 

  14. Herrera A, Ortega C, Reyes G, Alvarez MA, Tellez D. Primary orbital mesenchymal chondrosarcoma: case report and review of the literature. Case Rep Med. 2012;2012(4):Article ID 292147. doi:10.1155/2012/292147.

    Google Scholar 

  15. Aybar MD, Demirci I, Barut AY, Ozturk A. Extraskeletal chondrosarcoma of the inferior nasal concha. Eur J Radiol Extra. 2010;75(3):e93–e96.

    Article  Google Scholar 

  16. Barosa J, Ribeiro J, Afonso L, Fernandes J, Monteiro E. Head and neck sarcoma: analysis of 29 cases. Eur Ann Otorhinolaryngol Head Neck Dis. 2014;131:83–6.

    Article  CAS  PubMed  Google Scholar 

  17. Chen Y, Wang X, Guo L, et al. Radiological features and pathology of extraskeletal mesenchymal chondrosarcoma. Clin Imaging. 2012;36:365–70.

    Article  CAS  PubMed  Google Scholar 

  18. Guo L, Liu J, Sun X, Wang D. Sinonasal tract chondrosarcoma: 18-Year experience at a single institution. Auris Nasus Larynx. 2014;41:290–3.

    Article  PubMed  Google Scholar 

  19. Obeso S, Llorente JL, Díaz-Molina JP, et al. Surgical treatment of head and neck chondrosarcomas. Acta Otorrinolaringol Esp. 2010;61(4):262–71.

    Article  PubMed  Google Scholar 

  20. Romesser PB, Cahlon O, Scher E, et al. Proton beam radiation therapy results in significantly reduced toxicity compared with intensity-modulated radiation therapy for head and neck tumors that require ipsilateral radiation. Radiother Oncol. 2016;118(2):286–92. doi:10.1016/j.radonc.2015.12.008.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Allen AM, Pawlicki T, Dong L, et al. An evidence based review of proton beam therapy: the report of ASTRO’s emerging technology committee. Radiother Oncol. 2012;103:8–11.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Radiology Department, ENT-Head and Neck Surgery Service, General Hospital of Concepcion, Concepcion, Chile

    Ilson Sepúlveda

  2. Radiotherapy Department, Oncology Service, General Hospital of Concepcion, Concepcion, Chile

    Max Schorwer

  3. Oral and Maxillofacial Radiology, University of North Carolina School of Dentistry, Chapel Hill, NC, USA

    Enrique Platin

  4. Pathology Department, General Hospital of Concepción, University of Concepcion School of Medicine, Concepcion, Chile

    Pablo Mucientes

  5. ENT-Head and Neck Surgery Service, General Hospital of Concepcion, University of Concepcion School of Medicine, Concepcion, Chile

    Álvaro Compan, Joaquin Ulloa & Nestor Quitral

  6. Neurosurgery Service, General Hospital of Concepcion, Concepcion, Chile

    Jaime Pinto

Authors
  1. Ilson Sepúlveda
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Max Schorwer
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Enrique Platin
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Pablo Mucientes
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Álvaro Compan
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Joaquin Ulloa
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Jaime Pinto
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Nestor Quitral
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Ilson Sepúlveda.

Ethics declarations

Conflict of interest

I. Sepúlveda, M. Schorwer, E. Platin, P. Mucientes, Á. Compan, J. Ulloa, J. Pinto, and N. Quitral declare that they have no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sepúlveda, I., Schorwer, M., Platin, E. et al. Orbito-maxillofacial mesenchymal chondrosarcoma with intracranial invasion and lung metastasis. memo 10, 106–110 (2017). https://doi.org/10.1007/s12254-017-0323-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12254-017-0323-7

Keywords

Search

Navigation