Zusammenfassung
Im Juni 2013 wurden die neuen European Society of Hypertension (ESH)/European Society of Cardiology (ESC)-Leitlinien zum Management der arteriellen Hypertonie publiziert. Die Deutsche Hochdruckliga e.V. DHL®/Deutsche Gesellschaft für Hypertonie und Prävention und die Deutsche Gesellschaft für Kardiologie (DGK) haben sich erstmalig entschlossen, diese Leitlinien in Form praxisnaher Pocketleitlinien gemeinsam zu übersetzen. Die DHL/DGK-Pocketleitlinien sind eine genaue Übersetzung der ESH/ESC-Pocketleitlinien. Mit dem vorliegenden Kommentar, möchten wir über bedeutende Änderungen der neuen Leitlinien gegenüber den vorpublizierten Versionen informieren. Zusätzlich werden unter Berücksichtigung nationaler Rahmenbedingungen und der Bewertung durch DHL/DGK-Expertenkommissionen einzelne kontroverse ESH/ESC-Empfehlungen diskutiert. Insbesondere werden die Bedeutung der Blutdruckmessung außerhalb der Praxis, neue Zielblutdruckwerte, Änderungen in der medikamentösen Therapie und das Vorgehen bei therapieresistenter Hypertonie besprochen. Abschließend werden die Limitationen der aktuellen Leitlinien diskutiert.
Abstract
In June 2013 the European Society of Hypertension (ESH) and European Society of Cardiology (ESC) guidelines for the management of arterial hypertension were published. For the first time the German Hypertension League (DHL®), German Society of Hypertension and Prevention, and the German Society of Cardiology (DGK) decided to translate these guidelines as clinical practice pocket guidelines in a collaborative manner. The DHL/DGK pocket guidelines represent an exact translation of the ESH/ESC pocket guidelines. With the present comments we want to inform clinicians about important changes in the new guidelines. In consideration of the national regulatory environment, and after evaluation by DHL/DGK expert panels, selected controversial ESH/ESC recommendations will be discussed. In particular, the importance of out-of-office blood pressure measurements, new blood pressure targets, changes in antihypertensive drug therapy, and new approaches in resistant hypertension will be reviewed. Finally, the limitations of the current guidelines will be discussed.
Literatur
Mancia G, Fagard R, Narkiewicz K et al (2013) 2013 ESH/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens 31:1281–1357
Mancia G, Fagard R, Narkiewicz K et al (2013) 2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J 34:2159–2219
Lim SS, Vos T, Flaxman AD et al (2012) A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 380:2224–2260
Neuhauser H, Thamm M, Ellert U (2013) Blood pressure in Germany 2008–2011: results of the German Health Interview and Examination Survey for Adults (DEGS1). Bundesgesundheitsbl Gesundheitsforsch Gesundheitsschutz 56:795–801
Janhsen K, Strube H, Starker A (2008) Hypertonie. Gesundheitsberichterstattung des Bundes 43:1–35
Bliziotis IA, Destounis A, Stergiou GS (2012) Home versus ambulatory and office blood pressure in predicting target organ damage in hypertension: a systematic review and meta-analysis. J Hypertens 30:1289–1299
Ward AM, Takahashi O, Stevens R, Heneghan C (2012) Home measurement of blood pressure and cardiovascular disease: systematic review and meta-analysis of prospective studies. J Hypertens 30:449–456
Mancia G, De Backer G, Dominiczak A et al (2007) 2007 Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens 25:1105–1187
Schrier RW, Estacio RO, Esler A, Mehler P (2002) Effects of aggressive blood pressure control in normotensive type 2 diabetic patients on albuminuria, retinopathy and strokes. Kidney Int 61:1086–1097
McMurray JJ, Holman RR, Haffner SM et al (2010) Effect of valsartan on the incidence of diabetes and cardiovascular events. N Engl J Med 362:1477–1490
Zanchetti A, Grassi G, Mancia G (2009) When should antihypertensive drug treatment be initiated and to what levels should systolic blood pressure be lowered? A critical reappraisal. J Hypertens 27:923–934
UKPDS 38 (1998) Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. UK Prospective Diabetes Study Group. BMJ 317:703–713
Hansson L, Zanchetti A, Carruthers SG et al (1998) Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group. Lancet 351:1755–1762
Beckett NS, Peters R, Fletcher AE et al (2008) Treatment of hypertension in patients 80 years of age or older. N Engl J Med 358:1887–1898
Appel LJ, Wright JT, Greene T Jr et al (2010) Intensive blood-pressure control in hypertensive chronic kidney disease. N Engl J Med 363:918–929
Sarnak MJ, Greene T, Wang X et al (2005) The effect of a lower target blood pressure on the progression of kidney disease: long-term follow-up of the modification of diet in renal disease study. Ann Intern Med 142:342–351
Upadhyay A, Earley A, Haynes SM, Uhlig K (2011) Systematic review: blood pressure target in chronic kidney disease and proteinuria as an effect modifier. Ann Intern Med 154:541–548
Law MR, Morris JK, Wald NJ (2009) Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies. BMJ 338:b1665
Roush GC, Holford TR, Guddati AK (2012) Chlorthalidone compared with hydrochlorothiazide in reducing cardiovascular events: systematic review and network meta-analyses. Hypertension 59:1110–1117
Zanchetti A, Mancia G (2012) Longing for clinical excellence: a critical outlook into the NICE recommendations on hypertension management – is nice always good? J Hypertens 30:660–668
Parving HH, Brenner BM, McMurray JJ et al (2012) Cardiorenal end points in a trial of aliskiren for type 2 diabetes. N Engl J Med 367:2204–2213
Yusuf S, Teo KK, Pogue J et al (2008) Telmisartan, ramipril, or both in patients at high risk for vascular events. N Engl J Med 358:1547–1559
Gupta AK, Arshad S, Poulter NR (2010) Compliance, safety, and effectiveness of fixed-dose combinations of antihypertensive agents: a meta-analysis. Hypertension 55:399–407
Bhatt DL, Kandzari DE, O’Neill WW et al (2014) A controlled trial of renal denervation for resistant hypertension. N Engl J Med 370(15):1393–1401
Deutsche Gesellschaft für Kardiologie – Herz- und Kreislaufforschung e.V. (2014) ESC POCKET GUIDELINES. Leitlinien für das Management der arteriellen Hypertonie. Börm Bruckmeier, Grünwald (im Druck)
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Interessenkonflikt. Den Interessenkonflikt der Autoren finden Sie online auf der DGK-Homepage unter http://leitlinien.dgk.org/bei der entsprechenden Publikation. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.
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Kintscher, U., Böhm, M., Goss, F. et al. Kommentar zur 2013-ESH/ESC-Leitlinie zum Management der arteriellen Hypertonie. Kardiologe 8, 223–230 (2014). https://doi.org/10.1007/s12181-014-0575-y
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DOI: https://doi.org/10.1007/s12181-014-0575-y