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New Perspectives of Quantum Dots in the Food Field: Determination of β-Carotene in Tropical Fruit Juices and Food Supplements

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Abstract

A novel and simple method for the determination of β-carotene, a carotenoid abundant in plants and fruits, is proposed. Multicommutated flow injection analysis (MCFIA) has been applied as automated flow methodology to the analysis of β-carotene in tropical fruit juices and food supplements, making use of the quenching effect caused by this analyte over glutathione-capped CdTe quantum dots (QDs) fluorescence signal. Under optimized conditions, the method was linear in the range of 0.3–15 μg mL−1, with a detection limit of 0.09 μg mL−1 and relative standard deviations lower than 3%. The determination rate was of about 80 h−1, and results were in good agreement with those provided by both the manufacturer and a chromatographic reference method.

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References

  • Andrés V, Villanueva MJ, Tenorio MD (2014) Simultaneous determination of tocopherols, retinol, ester derivatives and β-carotene in milk- and soy-juice based beverages by HPLC with diode-array detection. LWT - Food Sci Technol 58:557–562

    Article  Google Scholar 

  • Brabcová I, Hlaváčková M, Šatínský D, Solich P (2013) A rapid HPLC column switching method for sample preparation and determination of β-carotene in food supplements. Food Chem 141:1433–1437

    Article  Google Scholar 

  • Costa-Fernandez JM, Pereiro R, Sanz-Medel A (2006) The use of luminescent quantum dots for optical sensing. Trac-Trend Anal Chem 25:207–218

    Article  CAS  Google Scholar 

  • Chiosa V, Mandravel C, Kleinjans JCS, Moonen E (2005) Determination of b-carotene concentration in orange and apple juice and in vitamin supplemented drinks. An Univ Bucuresti : Chimie 1-2:253–258

    Google Scholar 

  • De Nardo T, Shiroma-Kian C, Halim Y, Francis D, Rodriguez-Saona LE (2009) Rapid and simultaneous determination of lycopene and β-carotene contents in tomato juice by infrared spectroscopy. J Agr Food Chem 57:1105–1112

    Article  CAS  Google Scholar 

  • Frigerio C, Ribeiro DSM, Rodrigues SSM, Abreu VLRG, Barbosa JAC, Prior JAV, Marques KL, Santos JLM (2012) Application of quantum dots as analytical tools in automated chemical analysis: a review. Anal Chim Acta 735:9–22

    Article  CAS  Google Scholar 

  • Garewal HS, Schantz S (1995) EMerging role of β-carotene and antioxidant nutrients in prevention of oral cancer. Arch Otolaryngol Head Neck Surg 121:141–144

    Article  CAS  Google Scholar 

  • Giuffrida D, Torre G, Dugo P, Dugo G (2013) Determination of the carotenoid profile in peach fruits, juice and jam. Fruits 68:39–44

    Article  CAS  Google Scholar 

  • Group TA-TBCCPS (1994) The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med 330:1029–1035

    Article  Google Scholar 

  • Ji X, Palui G, Avellini T, Na HB, Yi C, Knappenberger KL, Mattoussi H (2012) On the pH-dependent quenching of quantum dot photoluminescence by redox active dopamine. J Am Chem Soc 134:6006–6017

    Article  CAS  Google Scholar 

  • Jimenez-López J, Molina-García L, Rodrigues SSM, Santos JLM, Ortega-Barrales P, Ruiz-Medina A (2016) Automated determination of rifamycins making use of MPA–CdTe quantum dots. J Lumin 175:158–164

    Article  Google Scholar 

  • Jiménez-López J, Ortega-Barrales P, Ruiz-Medina A (2016) Development of an semi-automatic and sensitive photochemically induced fluorescence sensor for the determination of thiamethoxam in vegetables. Talanta 149:149–155

    Article  Google Scholar 

  • Li Q, Tan X, Li J, Pan L, Liu X (2015) Glutathione-capped CdTe nanocrystals as probe for the determination of fenbendazole. Spectrochim Acta Part A Mol Biomol Spectrosc 141:10–15

    Article  CAS  Google Scholar 

  • Llorent-Martínez EJ, Molina-García L, Fernández-de Córdova ML, Santos JLM, Rodrigues SSM, Ruiz-Medina A (2013a) A novel multi-commutated method for the determination of hydroxytyrosol in enriched foods using mercaptopropionic acid-capped CdTe quantum dots. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 30:1485–1492

    Article  Google Scholar 

  • Llorent-Martínez EJ, Molina-García L, Kwiatkowski R, Ruiz-Medina A (2013b) Application of quantum dots in clinical and alimentary fields using multicommutated flow injection analysis. Talanta 109:203–208

    Article  Google Scholar 

  • Mayne ST (1996) Beta-carotene, carotenoids, and disease prevention in humans. FASEB J 10:690–701

    CAS  Google Scholar 

  • Melavanki RM, Kusanur RA, Kadadevaramath JS, Kulakarni MV (2009) Quenching mechanisms of 5BAMC by aniline in different solvents using Stern–Volmer plots. J Lumin 129:1298–1303

    Article  CAS  Google Scholar 

  • Molina-García L, Fernández-de Córdova ML, Ruiz-Medina A (2012) Analysis of bisphenol A in milk by using a multicommuted fluorimetric sensor. Talanta 96:195–201

    Article  Google Scholar 

  • Molina-García L, Llorent-Martínez EJ, Fernández-de Córdova ML, Santos JLM, Rodrigues SSM, Ruiz-Medina A (2013) Study of the quenching effect of quinolones over CdTe-quantum dots using sequential injection analysis and multicommutation. J Pharm Biomed Anal 80:147–154

    Article  Google Scholar 

  • Qian HF, Dong CQ, Weng JF, Ren JC (2006) Facile one-pot synthesis of luminescent, water-soluble, and biocompatible glutathione-coated CdTe nanocrystals. Small 2:747–751

    Article  CAS  Google Scholar 

  • Raymo FM, Yildiz I (2007) Luminescent chemosensors based on semiconductor quantum dots. Phys Chem Chem Phys 9:2036–2043

    Article  CAS  Google Scholar 

  • Rodrigues SSM, Ribeiro DSM, Molina-Garcia L, Ruiz Medina A, Prior JAV, Santos JLM (2014) Fluorescence enhancement of CdTe MPA-capped quantum dots by glutathione for hydrogen peroxide determination. Talanta 122:157–165

    Article  CAS  Google Scholar 

  • Ruedas-Rama MJ, Walters JD, Orte A, Hall EAH (2012) Fluorescent nanoparticles for intracellular sensing: a review. Anal Chim Acta 751:1–23

    Article  CAS  Google Scholar 

  • Rungpichayapichet P, Mahayothee B, Khuwijitjaru P, Nagle M, Müller J (2015) Non-destructive determination of β-carotene content in mango by near-infrared spectroscopy compared with colorimetric measurements. J Food Compos Anal 38:32–41

    Article  CAS  Google Scholar 

  • Xiangzhao A, Qiang M, Xingguang S (2013) Nanosensor for dopamine and glutathione based on the quenching and recovery of the fluorescence of silica-coated quantum dots. Microchim Acta 180:269–277

    Article  Google Scholar 

  • Yang Q, Tan X, Yang J (2015) Sensitive determination of enoxacin in pharmaceutical formulations by its quench effect on the fluorescence of glutathione-capped CdTe quantum dots. Luminescence 31:241–246

    Article  Google Scholar 

  • Yu WW, Qu LH, Guo WZ, Peng XG (2003) Experimental determination of the extinction coefficient of CdTe, CdSe, and CdS nanocrystals. Chem Mater 15:2854–2860

    Article  CAS  Google Scholar 

  • Yuan J, Guo W, Yin J, Wang E (2009) Glutathione-capped CdTe quantum dots for the sensitive detection of glucose. Talanta 77:1858–1863

    Article  CAS  Google Scholar 

  • Zou L, Gu Z, Zhang N, Zhang Y, Fang Z, Zhu W, Zhong X (2008) Ultrafast synthesis of highly luminescent green- to near infrared-emitting CdTe nanocrystals in aqueous phase. J Mater Chem 18:2807–2815

    Article  CAS  Google Scholar 

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Acknowledgements

J.J.L. acknowledges research scholarship from Spanish Government (“Ministerio de Educación y Ciencia”).

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Correspondence to A. Ruiz-Medina.

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Funding

This study was funded by the “Ministerio de Economía y Competitividad” (grant number CTQ2016-7511-R).

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J. Jiménez-López declares that she has no conflict of interest. J.L.M. Santos declares that he has no conflict of interest. P. Ortega-Barrales declares that she has no conflict of interest. A. Ruiz-Medina declares that he has no conflict of interest.

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This article does not contain any studies with human participants or animals performed by any of the authors.

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Jiménez-López, J., Santos, J., Ortega-Barrales, P. et al. New Perspectives of Quantum Dots in the Food Field: Determination of β-Carotene in Tropical Fruit Juices and Food Supplements. Food Anal. Methods 10, 2412–2421 (2017). https://doi.org/10.1007/s12161-017-0811-8

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  • DOI: https://doi.org/10.1007/s12161-017-0811-8

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