Skip to main content
Log in

Review and Meta-analysis of Couple-Oriented Interventions for Chronic Illness

  • Original Article
  • Published:
Annals of Behavioral Medicine

Abstract

Background

Evidence continues to build for the impact of the marital relationship on health as well as the negative impact of illness on the partner. Targeting both patient and partner may enhance the efficacy of psychosocial or behavioral interventions for chronic illness.

Purpose

The purpose of this report is to present a cross-disease review of the characteristics and findings of studies evaluating couple-oriented interventions for chronic physical illness.

Methods

We conducted a qualitative review of 33 studies and meta-analyses for a subset of 25 studies.

Results

Identified studies focused on cancer, arthritis, cardiovascular disease, chronic pain, HIV, and Type 2 diabetes. Couple interventions had significant effects on patient depressive symptoms (d = 0.18, p < 0.01, k = 20), marital functioning (d = 0.17, p < 0.01, k = 18), and pain (d = 0.19, p < 0.01, k = 14) and were more efficacious than either patient psychosocial intervention or usual care.

Conclusions

Couple-oriented interventions have small effects that may be strengthened by targeting partners’ influence on patient health behaviors and focusing on couples with high illness-related conflict, low partner support, or low overall marital quality. Directions for future research include assessment of outcomes for both patient and partner, comparison of couple interventions to evidence-based patient interventions, and evaluation of mechanisms of change.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. Kiecolt-Glaser JK, Newton TL. Marriage and health: His and hers. Psychological Bulletin. 2001;127:472-503.

    Article  PubMed  CAS  Google Scholar 

  2. Baker B, Helmers K, O'Kelly B, et al. Marital cohesion and ambulatory blood pressure in early hypertension. Am J Hypertens. 1999;12:227-230.

    Article  PubMed  CAS  Google Scholar 

  3. Rohrbaugh MJ, Shoham V, Coyne JC. Effect of marital quality on eight-year survival of patients with heart failure. Am J Cardiol. 2006;98:1069-1072.

    Article  PubMed  Google Scholar 

  4. Orth-Gomer K, Wamala SP, Horsten M, et al. Marital stress worsens prognosis in women with coronary heart disease: The Stockholm Female Coronary Risk Study. JAMA. 2000;284:3008-3014.

    Article  PubMed  CAS  Google Scholar 

  5. Weihs KL, Enright TM, Simmens SJ. Close relationships and emotional processing predict decreased mortality in women with breast cancer: Preliminary evidence. Psychosom Med. 2008;70:117-124.

    Article  PubMed  Google Scholar 

  6. Kimmel PL, Peterson RA, Weihs KL, et al. Dyadic relationship conflict, gender, and mortality in urban hemodialysis patients. J Am Soc Nephrol. 2000;11:1518-1525.

    PubMed  CAS  Google Scholar 

  7. Fisher L. Research on the family and chronic disease among adults: Major trends and directions. Families, Systems & Health. 2006;24:373-380.

    Article  Google Scholar 

  8. Martire LM, Schulz R. Caregiving and care-receiving in later life: Recent evidence for health effects and promising intervention approaches. In A. Baum, T. Revenson and J. Singer (eds), Handbook of Health Psychology. New York: Taylor & Francis, in press.

  9. Fredman L, Bertrand RM, Martire LM, Hochberg M, Harris EL. Leisure-time exercise and overall physical activity in older women caregivers and non-caregivers from the Caregiver-SOF Study. Prev Med. 2006;43:226-229.

    Article  PubMed  Google Scholar 

  10. Lee S, Colditz GA, Berkman LF, Kawachi I. Caregiving and risk of coronary heart disease in U.S. women: A prospective study. Am J Prev Med. 2003;24:113-119.

    Article  PubMed  Google Scholar 

  11. Schulz R, Beach SR. Caregiving as a risk factor for mortality: The caregiver health effects study. Journal of the American Medical Association. 1999;282:2215-2219.

    Article  PubMed  CAS  Google Scholar 

  12. Schulz R, Beach SR, Hebert RS, et al. Spousal suffering and partner's depression and cardiovascular disease: The Cardiovascular Health Study. Am J Geriatr Psychiatry. 2009;17:246-254.

    Article  PubMed  Google Scholar 

  13. Bolger N, Foster M, Vinokur AD, Ng R. Close relationships and adjustment to a life crisis: The case of breast cancer. J Pers Soc Psychol. 1996;70:283-294.

    Article  PubMed  CAS  Google Scholar 

  14. Revenson TA. Social support and marital coping with chronic illness. Ann Behav Med. 1994;16:122-130.

    Google Scholar 

  15. Stephens MAP, Martire LM, Cremeans-Smith JK, Druley JA, Wojno WC. Older women with osteoarthritis and their caregiving husbands: Effects of patients’ pain and pain expression. Rehabil Psychol. 2006;51:3-12.

    Article  Google Scholar 

  16. Fisher L, Chesla CA, Skaff MM, Mullan JT, Kanter RA. Depression and anxiety among partners of European-American and Latino patients with type 2 diabetes. Diabetes Care. 2002;25:1564-1570.

    Article  PubMed  Google Scholar 

  17. Gonder-Frederick LA, Cox DJ, Kovatchev B, Julian D, Clarke W. The psychosocial impact of severe hypoglycemic episodes on spouses of patients with IDDM. Diabetes Care. 1997;20:1543-1546.

    Article  PubMed  CAS  Google Scholar 

  18. Schmaling KB, Sher TG. The psychology of couples and illness: Theory, research, and practice. 1st ed. Washington, D.C.: American Psychological Association; 2000.

    Google Scholar 

  19. Dixon KE, Keefe FJ, Scipio CD, Perri LM, Abernethy AP. Psychological interventions for arthritis pain management in adults: A meta-analysis. Health Psychol. 2007;26:241-250.

    Article  PubMed  Google Scholar 

  20. Rees K, Bennett P, West R, Davey SG, Ebrahim S: Psychological interventions for coronary heart disease. Cochrane Database Syst Rev. 2004:CD002902.

  21. Scott-Sheldon LA, Kalichman SC, Carey MP, Fielder RL. Stress management interventions for HIV + adults: A meta-analysis of randomized controlled trials, 1989 to 2006. Health Psychol. 2008;27:129-139.

    Article  PubMed  Google Scholar 

  22. Jacobsen PB, Donovan KA, Vadaparampil ST, Small BJ. Systematic review and meta-analysis of psychological and activity-based interventions for cancer-related fatigue. Health Psychol. 2007;26:660-667.

    Article  PubMed  Google Scholar 

  23. Martire LM, Schulz R. Involving family in psychosocial interventions for chronic illness. Current Directions in Psychological Science. 2007;16:90-94.

    Article  Google Scholar 

  24. Cochrane BB, Lewis FM. Partner's adjustment to breast cancer: A critical analysis of intervention studies. Health Psychol. 2005;24:327-332.

    Article  PubMed  Google Scholar 

  25. Borenstein M, Hedges L, Higgins J, Rothstein H. Comprehensive Meta-analysis Version 2. Englewood, NJ: Biostat; 2005.

    Google Scholar 

  26. Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21:1539-1558.

    Article  PubMed  Google Scholar 

  27. Bucher HC, Guyatt GH, Griffith LE, Walter SD. The results of direct and indirect treatment comparisons in meta-analysis of randomized controlled trials. J Clin Epidemiol. 1997;50:683-691.

    Article  PubMed  CAS  Google Scholar 

  28. Baucom DH, Shoham V, Mueser KT, Daiuto AD, Stickle TR. Empirically supported couple and family interventions for marital distress and adult mental health problems. J Consult Clin Psychol. 1998;66:53-88.

    Article  PubMed  CAS  Google Scholar 

  29. Badger T, Segrin C, Dorros SM, Meek P, Lopez AM. Depression and anxiety in women with breast cancer and their partners. Nursing Research. 2007;56:44-53.

    Article  PubMed  Google Scholar 

  30. Hartford K, Wong C, Zakaria D. Randomized controlled trial of a telephone intervention by nurses to provide information and support to patients and their partners after elective coronary artery bypass graft surgery: Effects of anxiety. Heart & Lung. 2002;31:199-206.

    Article  Google Scholar 

  31. Mishel MH, Belyea M, Germino BB, et al. Helping patients with localized prostate carcinoma manage uncertainty and treatment side effects: Nurse-delivered psychoeducational intervention over the telephone. Cancer. 2002;94:1854-1866.

    Article  PubMed  Google Scholar 

  32. Keefe FJ, Ahles TA, Sutton L, et al. Partner-guided cancer pain management at the end of life: A preliminary study. Journal of Pain and Symptom Management. 2005;29:263-272.

    Article  PubMed  Google Scholar 

  33. Nezu AM, Nezu CM, Felgoise SH, McClure KS, Houts PS. Project Genesis: Assessing the efficacy of problem-solving therapy for distressed adult cancer patients. Journal of Consulting and Clinical Psychology. 2003;71:1036-1048.

    Article  PubMed  Google Scholar 

  34. Wadden TA. Predicting treatment response to relaxation therapy for essential hypertension. The Journal of Nervous and Mental Disease. 1989;171:683-689.

    Article  Google Scholar 

  35. Campbell LC, Keefe FJ, Scipio C, et al. Facilitating research participation and improving quality of life for African-American prostate cnacer survivors and their intimate partners. Cancer. 2007;109:414-424.

    Article  PubMed  Google Scholar 

  36. Gilliss CL, Neuhaus JM, Hauck WW. Improving family functioning after cardiac surgery: A randomized trial. Heart & Lung. 1990;19:648-654.

    CAS  Google Scholar 

  37. Gortner SR, Gilliss CL, Shinn JA, et al. Improving recovery following cardiac surgery: A randomized clinical trial. Journal of Advanced Nursing. 1988;13:649-661.

    Article  PubMed  CAS  Google Scholar 

  38. Lenz ER, Perkins S. Coronary artery bypass graft surgery patients and their family member caregivers: Outcomes of a family-focused staged psychoeducational intervention. Applied Nursing Research. 2000;13:142-150.

    Article  PubMed  CAS  Google Scholar 

  39. Northouse LL, Mood DW, Schafenacker A, et al. Randomized clinical trial of a family intervention for prostate cancer patients and their spouses. Cancer. 2007;110:2809-2818.

    Article  PubMed  Google Scholar 

  40. Scott JL, Halford WK, Ward BG. United we stand? The effects of a couple-coping intervention on adjustment to early stage breast or gynecological cancer. Journal of Consulting and Clinical Psychology. 2004;72:1122-1135.

    Article  PubMed  Google Scholar 

  41. Remien RH, Stirratt MJ, Dolezal C, et al. Couple-focused support to improve HIV medication adherence: A randomized controlled trial. AIDS. 2005;19:807-814.

    Article  PubMed  Google Scholar 

  42. Wing RR, Marcus MD, Epstein LH, Jawad A. A "family-based" approach to the treatment of obese Type II diabetic patients. Journal of Consulting and Clinical Psychology. 1991;59:156-162.

    Article  PubMed  CAS  Google Scholar 

  43. van Lankveld W, van Helmond T, Naring G, de Rooij DJ, van den Hoogen F. Partner participation in cognitive-behavioral self-management group treatment for patients with rheumatoid arthritis. Journal of Rheumatology. 2004;31:1738-1745.

    PubMed  Google Scholar 

  44. Fridlund B, Hogstedt B, Lidell E, Larsson PA. Recovery after myocardial infarction: Effects of a caring rehabilitation programme. Scandinavian Journal of Caring Science. 1991;5:23-32.

    CAS  Google Scholar 

  45. Riemsma RP, Taal E, Rasker J. Group education for patients with rheumatoid arthritis and their partners. Arthritis & Rheumatism. 2003;49:556-566.

    Article  Google Scholar 

  46. Baucom DH, Porter LS, Kirby JS, et al. A couple-based intervention for female breast cancer. Psychooncology. 2009;18:276-283.

    Article  PubMed  Google Scholar 

  47. Fife BL, Scott LL, Fineberg NS, Zwickl BE. Promoting adaptive coping by persons with HIV disease: Evaluation of a Patient/Partner Intervention Model. Journal of The Association of Nurses in AIDS Care. 2008;19:75-84.

    Article  PubMed  Google Scholar 

  48. Giesler RB, Given B, Given CW, et al. Improving the quality of life of patients with prostate carcinoma: A randomized trial testing the efficacy of a nurse-driven intervention. Cancer. 2005;104:752-762.

    Article  PubMed  Google Scholar 

  49. Kole-Snijders AMJ, Vlaeyen JWS, Goossens MEJB, et al. Chronic low-back pain: What does cognitive coping skills training add to operant behavioral treatment? Results of a Randomized Clinical Trial. Journal of Consulting and Clinical Psychology. 1999;67:931-944.

    Article  PubMed  CAS  Google Scholar 

  50. Kuijer RG, Buunk BP, De Jong GM, Ybema JF, Sanderman R. Effects of a brief intervention program for patients with cancer and their partners on feelings of inequity, relationship quality and psychological distress. Psycho-Oncology. 2004;13:321-334.

    Article  PubMed  Google Scholar 

  51. Manne SL, Ostroff JS, Winkel G, et al. Couple-focused group intervention for women with early stage breast cancer. Journal of Consulting and Clinical Psychology. 2005;73:634-646.

    Article  PubMed  Google Scholar 

  52. Manne S, Ostroff JS, Winkel G. Social-cognitive processes as moderators of a couple-focused group intervention for women with early stage breast cancer. Health Psychol. 2007;26:735-744.

    Article  PubMed  Google Scholar 

  53. Martire LM, Schulz R, Keefe FJ, et al. Feasibility of a dyadic intervention for management of osteoarthritis: A pilot study with older patients and their spousal caregivers. Aging & Mental Health. 2003;7:53-60.

    Article  CAS  Google Scholar 

  54. Moore JE, Chaney EF. Outpatient group treatment of chronic pain: Effects of spouse involvement. Journal of Consulting and Clinical Psychology. 1985;53:326-334.

    Article  PubMed  CAS  Google Scholar 

  55. Thompson DR, Meddis R. A prospective evaluation of in-hospital counselling for first time myocardial infarction men. Journal of Psychosomatic Research. 1990;34:237-248.

    Article  PubMed  CAS  Google Scholar 

  56. Turner JA, Clancy S, McQuade KJ, Cardenas DD. Effectiveness of behavioral therapy for chronic low back pain: A component analysis. Journal of Consulting and Clinical Psychology. 1990;58:573-579.

    Article  PubMed  CAS  Google Scholar 

  57. Saarijarvi S. A controlled study of couple therapy in chronic low back pain patients: Effects on marital satisfaction, psychological distress and health attitudes. Journal of Psychosomatic Research. 1991;35:265-272.

    Article  PubMed  CAS  Google Scholar 

  58. Canada AL, Neese LE, Sui D, Schover LR. Pilot intervention to enhance sexual rehabilitation for couples after treatment for localized prostate carcinoma. Cancer. 2005;104:2689-2700.

    Article  PubMed  Google Scholar 

  59. Christensen DN. Postmastectomy couple counseling: An outcome study of a structured treatment protocol. Journal of Sex and Marital Therapy. 1983;9:266-275.

    PubMed  CAS  Google Scholar 

  60. Martire LM, Schulz R, Keefe FJ, Rudy TE, Starz TW. Couple-oriented education and support intervention: Effects on individuals with osteoarthritis and their spouses. Rehabilitation Psychology. 2007;52:121-132.

    Article  Google Scholar 

  61. Martire LM, Schulz R, Keefe FJ, Rudy TE, Starz TW. Couple-oriented education and support intervention for osteoarthritis: Effects on spouses’ support and responses to patient pain. Families, Systems & Health. 2008;26:185-195.

    Article  Google Scholar 

  62. Keefe FJ, Caldwell DS, Baucom D, et al. Spouse-assisted coping skills training in the management of osteoarthritic knee pain. Arthritis Care and Research. 1996;9:279-291.

    Article  PubMed  CAS  Google Scholar 

  63. Keefe FJ, Caldwell DS, Baucom D, et al. Spouse-assisted coping skills training in the management of knee pain in osteoarthritis: Long-term followup results. Arthritis Care and Research. 1999;12:101-111.

    Article  PubMed  CAS  Google Scholar 

  64. Radojevic V, Nicassio PM, Weisman MH. Behavioral intervention with and without family support for rheumatoid arthritis. Behavior Therapy. 1992;23:13-30.

    Article  Google Scholar 

  65. Keefe FJ, Blumenthal J, Baucom D, et al. Effects of spouse-assisted coping skills training and exercise training in patients with osteoarthritis knee pain: A randomized controlled study. Pain. 2004;110:539-549.

    Article  PubMed  Google Scholar 

  66. Thompson DR, Meddis R. Wives' responses to counselling early after myocardial infarction. Journal of Psychosomatic Research. 1990;34:249-258.

    Article  PubMed  CAS  Google Scholar 

  67. Saarijarvi S, Alanen E, Rytokoski, Hyyppa MT. Couple therapy improves mental well-being in chronic low back pain patients: A controlled, five year follow-up study. Journal of Psychosomatic Research. 1992;36:651-656.

    Article  PubMed  CAS  Google Scholar 

  68. Hedges LV, Pigott TD. The power of statistical tests in meta-analysis. Psychol Methods. 2001;6:203-217.

    Article  PubMed  CAS  Google Scholar 

  69. Radloff LS. The CES–D scale: A self-report depression scale for research in the general population. Applied Psychological Measurement. 1977;1:385-401.

    Article  Google Scholar 

  70. Derogatis LR, Melisaratos N. The Brief Symptom Inventory: An introductory report. Psychol Med. 1983;13:595-605.

    Article  PubMed  CAS  Google Scholar 

  71. Spanier GB. Measuring dyadic adjustment: New scales for assessing the quality of marriage and similar dyads. Journal of Marriage and the Family. 1976;38:15-28.

    Article  Google Scholar 

  72. Kerns RD, Turk DC, Rudy TE. The West Haven-Yale Multidimensional Pain Inventory (WHYMPI). Pain. 1985;23:345-356.

    Article  PubMed  CAS  Google Scholar 

  73. Revenson TA, Schiaffino KM, Majerovitz SD, Gibofsky A. Social support as a double-edged sword: The relation of positive and problematic support to depression among rheumatoid arthritis patients. Soc Sci Med. 1991;33:807-813.

    Article  PubMed  CAS  Google Scholar 

  74. Meenan RF, Mason JH, Anderson JJ, Guccione AA, Kazis LE. AIMS2. The content and properties of a revised and expanded Arthritis Impact Measurement Scales Health Status Questionnaire. Arthritis Rheum. 1992;35:1-10.

    Article  PubMed  CAS  Google Scholar 

  75. Statistics NCfH: Health, United States, 2009: With Special Feature on Medical Technology. Hyattsville, MD: U.S. Government Printing Office, 2010.

  76. Lorig KR, Ritter P, Stewart AL, et al. Chronic disease self-management program: 2-year health status and health care utilization outcomes. Med Care. 2001;39:1217-1223.

    Article  PubMed  CAS  Google Scholar 

  77. Cella D, Yount S, Rothrock N, et al. The Patient-Reported Outcomes Measurement Information System (PROMIS): Progress of an NIH Roadmap cooperative group during its first two years. Med Care. 2007;45:S3-S11.

    Article  PubMed  Google Scholar 

  78. Christakis NA, Fowler JH. The spread of obesity in a large social network over 32 years. N Engl J Med. 2007;357:370-379.

    Article  PubMed  CAS  Google Scholar 

  79. Franks MM, Pienta AM, Wray LA. It takes two: Marriage and smoking cessation in the middle years. J Aging Health. 2002;14:336-354.

    Article  PubMed  Google Scholar 

  80. Pettee KK, Brach JS, Kriska AM, et al. Influence of marital status on physical activity levels among older adults. Med Sci Sports Exerc. 2006;38:541-546.

    Article  PubMed  Google Scholar 

  81. Williams GC, Lynch MF, McGregor HA, et al. Validation of the "Important Other" Climate Questionnaire: Assessing autonomy support for health-related change. Families, Systems & Health. 2006;24:179-194.

    Article  Google Scholar 

  82. Lewis MA, Butterfield RM. Antecedents and reactions to health-related social control. Pers Soc Psychol Bull. 2005;31:416-427.

    Article  PubMed  Google Scholar 

  83. Black DR, Gleser LJ, Kooyers KJ. A meta-analytic evaluation of couples weight-loss programs. Health Psychol. 1990;9:330-347.

    Article  PubMed  CAS  Google Scholar 

  84. Jeffery RW, Drewnowski A, Epstein LH, et al. Long-term maintenance of weight loss: Current status. Health Psychol. 2000;19:5-16.

    Article  PubMed  CAS  Google Scholar 

  85. Cohen S, Lichtenstein E, Mermelstein R, et al. Social support interventions for smoking cessation. In: Gottlieb BH, ed. Marshaling social support: Formats, processes, and effects. Newbury Park, CA: Sage; 1988:211-240.

    Google Scholar 

  86. Park EW, Schultz JK, Tudiver FG, Campbell C, Becker LA: Enhancing partner support to improve smoking cessation. Cochrane Database of Systematic Reviews. 2004, Issue 3.

  87. Shoham V, Rohrbaugh MJ, Trost SE, Muramoto M. A family consultation intervention for health-compromised smokers. J Subst Abuse Treat. 2006;31:395-402.

    Article  PubMed  Google Scholar 

  88. Davidson KW, Goldstein M, Kaplan RM, et al. Evidence-based behavioral medicine: What is it and how do we achieve it? Ann Behav Med. 2003;26:161-171.

    Article  PubMed  Google Scholar 

  89. Moher D, Schulz KF, Altman D. The CONSORT statement: Revised recommendations for improving the quality of reports of parallel-group randomized trials. JAMA. 2001;285:1987-1991.

    Article  PubMed  CAS  Google Scholar 

  90. Schulz R, Czaja SJ, McKay JR, Ory MG, Belle SH: Intervention taxonomy (ITAX): Describing essential features of interventions. American Journal of Health Behavior. in press.

  91. Kazdin AE, Bass D. Power to detect differences between alternative treatments in comparative psychotherapy outcome research. J Consult Clin Psychol. 1989;57:138-147.

    Article  PubMed  CAS  Google Scholar 

  92. Bolger N, Zuckerman A, Kessler RC. Invisible support and adjustment to stress. J Pers Soc Psychol. 2000;79:953-961.

    Article  PubMed  CAS  Google Scholar 

  93. Berg CA, Upchurch R. A developmental-contextual model of couples coping with chronic illness across the adult life span. Psychol Bull. 2007;133:920-954.

    Article  PubMed  Google Scholar 

  94. Bodenmann G. Dyadic coping and its significance for marital functioning. In: Revenson TA, Kayser K, Bodenmann G, eds. Couples coping with stress: Emerging perspectives on dyadic coping. Washington, DC: American Psychological Association; 2005:33-50.

    Chapter  Google Scholar 

  95. Lyons RF, Sullivan MJL, Ritvo PG, Coyne JC. Relationships in chronic illness and disability. Thousand Oaks: Sage Publications; 1995.

    Google Scholar 

  96. Kenny DA, Kashy DA, Cook WL. Dyadic Data Analysis. New York, NY: Cambridge University Press; 2006.

    Google Scholar 

  97. McArdle JJ, Hamagami F. Latent difference score structural models for linear dynamic analyses with incomplete longitudinal data. In: Collins LM, Sayer AG, eds. New methods for the analysis of change. Washington, DC: American Psychological Association; 2001:137-176.

    Google Scholar 

  98. Cohen S. Psychosocial models of the role of social support in the etiology of physical disease. Health Psychology. 1988;7:269-297.

    Article  PubMed  CAS  Google Scholar 

  99. Uchino BN. Social support and health: A review of physiological processes potentially underlying links to disease outcomes. J Behav Med. 2006;29:377-387.

    Article  PubMed  Google Scholar 

  100. Bookwala J, Schulz R. Spousal similarity in subjective well-being: The Cardiovascular Health Study. Psychol Aging. 1996;11:582-590.

    Article  PubMed  CAS  Google Scholar 

  101. Nock MK, Janis IB, Wedig MM. Research designs. In: Nezu AM, Nezu CM, eds. Evidence-Based. Outcome Research: A Practical Guide to Conducting Randomized Controlled Trials for Psychosocial Interventions Oxford University Press; 2008:201-218.

    Google Scholar 

Download references

Conflict of Interest Statement

The authors have no conflict of interest to disclose.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Lynn M. Martire Ph.D..

Additional information

References marked with an asterisk indicate studies included in the meta-analyses.

This research was supported in part by Grants R01 AG026010, R01 NR009573, and R01 DK060586.

About this article

Cite this article

Martire, L.M., Schulz, R., Helgeson, V.S. et al. Review and Meta-analysis of Couple-Oriented Interventions for Chronic Illness. ann. behav. med. 40, 325–342 (2010). https://doi.org/10.1007/s12160-010-9216-2

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12160-010-9216-2

Keywords

Navigation