Case Report

Annals of Nuclear Medicine

, Volume 22, Issue 3, pp 215-219

First online:

Extrapancreatic F-18 FDG accumulation in autoimmune pancreatitis

  • Motohiro SatoAffiliated withDepartment of Radiology, Ibaraki Prefectural Central Hospital Email author 
  • , Toshiyuki OkumuraAffiliated withDepartment of Radiology, Ibaraki Prefectural Central Hospital
  • , Yasukazu ShioyamaAffiliated withDepartment of Radiology, Ibaraki Prefectural Central Hospital
  • , Jyouji ImuraAffiliated withDepartment of Pathology, Ibaraki Prefectural Central Hospital

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We report two cases of autoimmune pancreatitis (AIP) in which fluorine-18 fluorodeoxyglucose (FDG) showed moderate accumulation in the pancreas, as well as in bilateral submandibular glands and in multifocal lymph nodes. FDG positron emission tomography (PET)/computed tomography (CT) is a useful diagnostic tool to assess the extrapancreatic lesions of AIP, which is a recently proposed new clinicopathological entity named immunoglobulin G4 (IgG4)-related systemic disease. Recognition of the FDG-PET/CT findings of IgG4-related sclerosing disease is crucial to avoid unnecessary surgery or other intervention because of similarities to malignant lymphoma or malignant tumor with multiple lymph node metastases.


Autoimmune pancreatitis (AIP) Sclerosing sialoadenitis IgG4-related sclerosing disease Positron emission tomography (PET) Fluorine-18 fluorodeoxyglucose (F-18 FDG)