Abstract
We present an example of clear cell chondrosarcoma (CCC) arising in the thyroid cartilage, and review the literature regarding this neoplasm in the larynx. This patient has no evidence of disease 3 years post hemilaryngectomy. Although rare and morphologically distinct, CCC follows the same benign clinical course as conventional laryngeal chondrosarcoma.
References
Thompson LD, Gannon FH. Chondrosarcoma of the larynx: a clinicopathologic study of 111 cases with a review of the literature. Am J Surg Pathol. 2002;26:836–51.
Baatenburg de Jong RJ, van Lent S, et al. Chondroma and chondrosarcoma of the larynx. Curr Opin Otolaryngol Head Neck Surg. 2004;12:98–105.
Rinaldo A, Howard DJ, Ferlito A. Laryngeal chondrosarcoma: a 24-year experience at the Royal National Throat, Nose, and Ear Hospital. Acta Otolaryngol. 2000;120:680–8.
Dubal PM, Svider PF, Kanumuri VV et al. Laryngeal chondrosarcoma: a population-based analysis. Laryngoscope. 2014. doi:10.1002/lary.24618.
Travers F. A case of ossification and bony growth of the cartilages of the larynx preventing deglutition. Med Chir Trans. 1816;7:150–1.
New GB. Sarcoma of the larynx: report of two cases. Arch Otolaryngol. 1935;21:648–52.
Obenauer S, Kunze E, Fischer U, et al. Unusual chondrosarcoma of the larynx: CT findings. Eur Radiol. 1999;9:1625–8.
Said S, Civantos F, Whiteman M, et al. Clear cell chondrosarcoma of the larynx. Otolaryngol Head Neck Surg. 2001;125:107–8.
Kleist B, Poetsch M, Lang C, et al. Clear cell chondrosarcoma of the larynx: a case report of a rare histologic variant in an uncommon localization. Am J Surg Pathol. 2002;26:386–92.
Kollert M, Basten O, Delling G, et al. Clear cell chondrosarcoma of the larynx: a rare tumor in an uncommon location. HNO. 2005;53:357–60.
Unni KK, Dahlin DC, Beabout JW, et al. Chondrosarcoma: clear-cell variant. A report of sixteen cases. J Bone Joint Surg Am. 1976;58:676–83.
Slootweg PJ. Clear-cell chondrosarcoma of the maxilla: report of a case. Oral Surg Oral Med Oral Pathol. 1980;50:233–7.
Euteneuer S, Sudhoff H, Stein H, et al. Clear cell chondrosarcoma of the nasal septum. Laryngorhinootologie. 2004;83(4):232–5.
Kim TJ, Lee AH, Choi YJ, et al. Clear cell chondrosarcoma in the nasal septum. Otolarynol Head Neck. 2007;137:972–3.
Mokhtari S, Mirafsharieh A. Clear cell chondrosarcoma of the head and neck. Head Neck Oncol. 2012;4:13.
Matsuura S, Ishii T, Endo M, et al. Epithelial and cartilaginous differentiation in clear cell chondrosarcoma. Hum Pathol. 2013;44:237–43.
Meijer D, de Jong D, Pansuriya TC, et al. Genetic characterization of mesenchymal, clear cell, and dedifferentiated chondrosarcoma. Genes Chromosomes Cancer. 2012;51:899–909.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Alexander, J., Wakely, P.E. Primary Laryngeal Clear Cell Chondrosarcoma: Report of a Case and Literature Review. Head and Neck Pathol 8, 307–310 (2014). https://doi.org/10.1007/s12105-014-0542-8
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12105-014-0542-8