The Indian Journal of Pediatrics

, Volume 80, Issue 8, pp 659–662

Prevalence and Risk Factors for Hepatitis C Virus, Hepatitis B Virus, and Human Immunodeficiency Virus in Transfused Children in Kinshasa

  • M. Katabuka
  • M. E. Mafuta
  • A. M. Ngoma
  • P. Mutombo Beya
  • S. Yuma
  • L. Aketi
  • K. P. Kayembe
  • J. R. Gini
Original Article

DOI: 10.1007/s12098-012-0899-1

Cite this article as:
Katabuka, M., Mafuta, M.E., Ngoma, A.M. et al. Indian J Pediatr (2013) 80: 659. doi:10.1007/s12098-012-0899-1

Abstract

Objective

To determine seroprevalence of hepatitis C virus (HCV), human immunodeficiency virus (HIV), and hepatitis B virus (HBV) and associated factors among transfused children.

Methods

A multicenter cross-sectional study of transfused children aged between 18 mo and 13 y old was conducted in 4 hospitals in Kinshasa. Blood samples were collected for the detection of Hepatitis B surface antigen (HBsAg) and antibodies to HCV, HIV 1and 2.

Results

A total of 177 (47.7 %) boys and 194 (52.3 %) girls participated in the study. The median age was 59.5 mo (Interquartile range IQR = 60.6). The prevalence rates of HCV, HBV, and HIV infection were 13.5 %, 1.6 %, and 1.3 %, respectively. Frequency of transfusion events were significantly associated with HCV (p < 0.001) and HIV (p < 0.05) infections.

Conclusions

HCV infection was by far more frequently identified than HBV and HIV infections among Congolese transfused children. Frequency of transfusion events was the only significant risk factor associated with HCV and HIV infections but not for HBV.

Keywords

Hepatitis C virusHuman immunodeficiency virusHepatitis B virusTransfusionChildren

Copyright information

© Dr. K C Chaudhuri Foundation 2012

Authors and Affiliations

  • M. Katabuka
    • 1
  • M. E. Mafuta
    • 2
  • A. M. Ngoma
    • 3
    • 6
  • P. Mutombo Beya
    • 4
  • S. Yuma
    • 5
  • L. Aketi
    • 1
  • K. P. Kayembe
    • 2
  • J. R. Gini
    • 1
  1. 1.Department of PediatricsUniversity of Kinshasa School of MedicineKinshasaJapan
  2. 2.School of Public HealthUniversity of Kinshasa School of MedicineKinshasaJapan
  3. 3.Department of Blood Transfusion and Transplantation ImmunologyFukushima Medical University School of MedicineFukushimaJapan
  4. 4.Department of Environmental and Preventive MedicineShimane UniversityShimaneJapan
  5. 5.Blood Transfusion National ProgramFukushimaJapan
  6. 6.Department of Transfusion Medicine and Transplantation ImmunologySchool of Medicine, Fukushima Medical UniversityFukushima CityJapan