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Successful Engraftment and Survival Following Allogeneic Hematopoietic Stem Cell Transplant in a Child with Familial Hemophagocytic Lymphohistiocytosis

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Abstract

Hemophagocytic syndrome is a rare disorder mainly affecting children. Symptoms include prolonged fever, hepatosplenomegaly and cytopenias. Allogeneic stem cell transplant appears to provide the best overall cure rate in this disease. The authors report a young boy, the second child of consanguineous parents, diagnosed with familial hemophagocytic lymphohistiocytosis (HLH) who underwent allogeneic stem cell transplant form HLA matched father.

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Authors and Affiliations

  1. Section of Hematology, Department of Pathology and Microbiology, The Aga Khan University and Hospital, Stadium Road 74800, P O Box 3500, Karachi, Pakistan

    Natasha Ali & Salman Naseem Adil

  2. Department of Pediatrics, The Aga Khan University and Hospital, Karachi, Pakistan

    Zehra Fadoo

  3. Department of Internal Medicine, The Aga Khan University and Hospital, Karachi, Pakistan

    Nehal Masood

Authors
  1. Natasha Ali
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  2. Zehra Fadoo
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  3. Nehal Masood
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  4. Salman Naseem Adil
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Correspondence to Natasha Ali.

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Ali, N., Fadoo, Z., Masood, N. et al. Successful Engraftment and Survival Following Allogeneic Hematopoietic Stem Cell Transplant in a Child with Familial Hemophagocytic Lymphohistiocytosis. Indian J Pediatr 80, 65–66 (2013). https://doi.org/10.1007/s12098-011-0658-8

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  • DOI: https://doi.org/10.1007/s12098-011-0658-8

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