Symposium on AIIMS Protocols in Neonatology

The Indian Journal of Pediatrics

, Volume 79, Issue 4, pp 501-509

Retinopathy of Prematurity

  • Deepak ChawlaAffiliated withDepartment of Pediatrics, Government Medical College
  • , Ramesh AgarwalAffiliated withDivision of Neonatology & WHO Collaborating Centre for Training & Research in Newborn Care, Department of Pediatrics, All India Institute of Medical Sciences
  • , Ashok DeorariAffiliated withDivision of Neonatology & WHO Collaborating Centre for Training & Research in Newborn Care, Department of Pediatrics, All India Institute of Medical SciencesDepartment of Pediatrics, All India Institute of Medical Sciences Email author 
  • , Vinod K. PaulAffiliated withDivision of Neonatology & WHO Collaborating Centre for Training & Research in Newborn Care, Department of Pediatrics, All India Institute of Medical Sciences
  • , Parijat ChandraAffiliated withDepartment of Ophthalmology, Dr. R. P. Centre for Ophthalmic Sciences, All India Institute of Medical Sciences
  • , Rajvardhan V. AzadAffiliated withDepartment of Ophthalmology, Dr. R. P. Centre for Ophthalmic Sciences, All India Institute of Medical Sciences

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Abstract

Retinopathy of prematurity (ROP) occurs due to abnormal proliferation of retinal vessels. The most important risk factors which predispose to development of ROP include oxygen therapy, anemia needing blood transfusion, sepsis and apnea. Very low birth weight neonates, those born at ≤32 week of gestation and other preterm neonates with risk factors must be screened for ROP. As a general rule first screening should be done at 1 month of postnatal age. If screening detects ROP not needing treatment follow up should be planned according to location and stage of ROP. Better visual outcomes are observed with earlier treatment at lower threshold. Peripheral retinal ablation with diode laser under adequate analgesia and sedation is the preferred method for treatment of severe ROP. Guidelines regarding the procedure of dilatation, ophthalmic examination and treatment (if required) have been provided in the protocol. Close co-operation between the ophthalmologist and neonatologist is essential for successful management of ROP.

Keywords

Prematurity Risk factors Retinopathy of prematurity