Clinical and Translational Oncology

, Volume 9, Issue 9, pp 563–570

Peptidomimetics in cancer chemotherapy

Educational Series

DOI: 10.1007/s12094-007-0104-6

Cite this article as:
Avendaño, C. & Menéndez, J.C. Clin Transl Oncol (2007) 9: 563. doi:10.1007/s12094-007-0104-6

Abstract

A summary of the current status of the application of peptidomimetics in cancer therapeutics as an alternative to peptide drugs is provided. Only compounds that are used in therapy or at least under clinical trials are discussed, using inhibitors of farnesyltransferase, proteasome and matrix metalloproteinases as examples.

Key words

Farnesyltransferase inhibitorsRasMetalloproteinase inhibitorsAngiogenesisProteasome inhibitors

Copyright information

© Feseo 2007

Authors and Affiliations

  1. 1.Departamento de Química Orgánica y FarmacéuticaUniversidad ComplutenseMadridSpain