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A multicellular signal transduction network of AGE/RAGE signaling

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Fig. 1

Abbreviations

RAGE:

Receptor for advanced glycation end products

HMGB1:

High mobility group box protein 1

sRAGE:

Soluble RAGE

CML:

N(6)(carboxymethyl)lysine

CEL:

N(6)(carboxyethyl)lysine

MMPs:

Matrix metalloproteinases

PTMs:

Post-translational modifications

PPIs:

Protein-protein interactions

BioPAX:

Biological PAthway eXchange

SBML:

Systems Biology Markup Language

PSI-MI:

Proteomics Standards Initiative for Molecular Interaction

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Acknowledgments

We thank the Department of Biotechnology (DBT), Government of India for research support to the Institute of Bioinformatics, Bangalore. Varot K. Sandhya is a recipient of INSPIRE Fellowship from the Department of Science and Technology, Government of India. H. C. Harsha is a Wellcome Trust-DBT India Alliance Early Career Fellow.

Conflict of interests

The author(s) declared no conflicts of interests.

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Authors and Affiliations

  1. Institute of Bioinformatics, International Technology Park, Bangalore, 560066, India

    Sowmya Soman, Rajesh Raju, Varot K. Sandhya, Jayshree Advani, Aafaque Ahmad Khan, H. C. Harsha, T. S. Keshava Prasad & Puneeth K. Adishesha

  2. Department of Computational Biology and Bioinformatics, State Inter-University Centre of Excellence in Bioinformatics, University of Kerala, Thiruvananthapuram, 695581, India

    P. R. Sudhakaran

  3. McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, 21205, MD, USA

    Akhilesh Pandey

  4. Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, 21205, MD, USA

    Akhilesh Pandey

  5. Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, 21205, MD, USA

    Akhilesh Pandey

  6. Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, 21205, MD, USA

    Akhilesh Pandey

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  1. Sowmya Soman
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  2. Rajesh Raju
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Corresponding author

Correspondence to Puneeth K. Adishesha.

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Sowmya Soman and Rajesh Raju contributed equally

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Soman, S., Raju, R., Sandhya, V.K. et al. A multicellular signal transduction network of AGE/RAGE signaling. J. Cell Commun. Signal. 7, 19–23 (2013). https://doi.org/10.1007/s12079-012-0181-3

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