Skip to main content

Advertisement

SpringerLink
Log in

Epithelial Myoepithelial Carcinoma of Parotid Gland

  • Clinical Report
  • Published:
Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

Epithelial myoepithelial carcinoma (EMC) is a rare biphasic tumor of salivary glands with low malignant potential. Although known to occur in submandibular gland and minor salivary glands, its most common location is parotid. Clinical and radiological findings often mimic a benign tumor. Because of rarity of EMC a standard treatment guideline is not yet known. Surgical resection is the most widely used approach. Although it is a low grade tumor, local recurrence rates of 23–50 % have been reported with 25 % chance of distant metastasis. Patients with histo-pathologic markers of aggressive disease should be considered for adjuvant radiotherapy. We report a case of epithelial myoepithelial carcinoma of parotid in a 40 year male that was treated with surgery followed by post-operative radiotherapy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

References

  1. Politi M, Robiony M, Avellini C, Orsaria M (2014) Epithelial–myoepithelial carcinoma of the parotid gland: clinicopathological aspect, diagnosis and surgical consideration. Ann Maxillofac Surg 4:99–102

    Article  Google Scholar 

  2. Halperin EC, Wazer DE, Parez CA, Brady LW (2013) Perez and Brady’s principles and practice of radiation oncology, 6th edn. Lippincott Williams & Wilkins, Philadelphia

    Google Scholar 

  3. Taş A, Yağiz R, Altaner S, Koten M, Karasalihoğlu AR (2003) A case of epithelial–myoepithelial carcinoma of the parotid gland. Kulak Burun Boğaz Ihtis Derg KBB J Ear Nose Throat 10(4):171–174

    Google Scholar 

  4. Sharma S, Patankar S (2014) An unusual case of epithelial–myoepithelial carcinoma of the parotid gland radiologically simulating a benign lesion. J Oral Maxillofac Pathol JOMFP. 18(1):118–120

    Article  Google Scholar 

  5. Simpson RH, Clarke TJ, Sarsfield PT, Gluckman PG (1991) Epithelial–myoepithelial carcinoma of salivary glands. J Clin Pathol 44(5):419–423

    Article  CAS  Google Scholar 

  6. Batsakis JG, El-Naggar AK, Luna MA (1992) Epithelial–myoepithelial carcinoma of salivary glands. Ann Otol Rhinol Laryngol 101(6):540–542

    Article  CAS  Google Scholar 

  7. Morrow TA, Chun T, Mirani N (1990) Epithelial myoepithelial carcinoma of the parotid gland. Ear Nose Throat J 69(9):646–648

    CAS  PubMed  Google Scholar 

  8. Puri T, Singh K, Sharma DN, Khurana N (2004) Epithelial–myoepithelial carcinoma of the base of tongue: pathology and management. Indian J Cancer 41(3):138–140

    PubMed  Google Scholar 

  9. Roy P, Bullock MJ, Perez-Ordoñez B, Dardick I, Weinreb I (2010) Epithelial–myoepithelial carcinoma with high grade transformation. Am J Surg Pathol 34(9):1258–1265

    Article  Google Scholar 

  10. Kusafuka K, Takizawa Y, Ueno T, Ishiki H, Asano R, Kamijo T et al (2008) Dedifferentiated epithelial–myoepithelial carcinoma of the parotid gland: a rare case report of immunohistochemical analysis and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol 106(1):85–91

    Article  Google Scholar 

  11. Noel S, Brozna JP (1992) Epithelial–myoepithelial carcinoma of salivary gland with metastasis to lung: report of a case and review of the literature. Head Neck 14(5):401–406

    Article  CAS  Google Scholar 

  12. Arora SK, Sharma N, Bhardwaj M (2013) Epithelial myoepithelial carcinoma of head and neck region. Indian J Otolaryngol Head Neck Surg 65(Suppl 1):163–166

    Article  Google Scholar 

  13. Savera AT, Sloman A, Huvos AG, Klimstra DS (2000) Myoepithelial carcinoma of the salivary glands: a clinicopathologic study of 25 patients. Am J Surg Pathol 24(6):761–774

    Article  CAS  Google Scholar 

  14. Takahashi H, Fujita S, Tsuda N, Tezuka F, Okabe H (1990) Intraoral minor salivary gland tumors: a demographic and histologic study of 200 cases. Tohoku J Exp Med 161(2):111–128

    Article  CAS  Google Scholar 

  15. Cho KJ, El-Naggar AK, Ordonez NG, Luna MA, Austin J, Batsakis JG (1995) Epithelial–myoepithelial carcinoma of salivary glands. A clinicopathologic, DNA flow cytometric, and immunohistochemical study of Ki-67 and HER-2/neu oncogene. Am J Clin Pathol 103(4):432–437

    Article  CAS  Google Scholar 

  16. Tralongo V, Daniele E (1998) Epithelial–myoepithelial carcinoma of the salivary glands: a review of literature. Anticancer Res 18(1B):603–608

    CAS  PubMed  Google Scholar 

  17. Seethala RR, Barnes EL, Hunt JL (2007) Epithelial–myoepithelial carcinoma: a review of the clinicopathologic spectrum and immunophenotypic characteristics in 61 tumor of salivary glands and upper aerodigestive tract. Am J Surg Pathol 31:44–57

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiation Oncology, Dr. BRA Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, 110029, India

    Pritee Chaudhari, Jaspreet Kaur, Suman Bhasker & Subhash Chander

  2. Department of Pathology, All India Institute of Medical Sciences, New Delhi, 110029, India

    Aasma Nalwa & Vaishali Suri

  3. Department of Radio Diagnosis, All India Institute of Medical Sciences, New Delhi, 110029, India

    Ananya Panda

Authors
  1. Pritee Chaudhari
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jaspreet Kaur
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Aasma Nalwa
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Vaishali Suri
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Ananya Panda
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Suman Bhasker
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Subhash Chander
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jaspreet Kaur.

Ethics declarations

Conflict of interest

None.

Informed Consent

Informed consent was obtained from the patient included in this case report.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Chaudhari, P., Kaur, J., Nalwa, A. et al. Epithelial Myoepithelial Carcinoma of Parotid Gland. Indian J Otolaryngol Head Neck Surg 71 (Suppl 1), 62–65 (2019). https://doi.org/10.1007/s12070-016-1025-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12070-016-1025-x

Keywords

Search

Navigation