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Questionable Necessity for Removing Submandibular Gland in Neck Dissection in Squamous Cell Carcinoma of Oral Cavity

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Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

To assess whether submandibular gland is involved by metastasis in cases of oral cavity squamous cell carcinomas. It was a retrospective study, where we reviewed the records of the patients who underwent neck dissections for Squamous Cell Carcinoma of the oral cavity. It included 112 patients who had undergone 115 neck dissections (three patients had undergone bilateral neck dissection), either therapeutic or prophylactic. No pathologic evidence of metastasis to submandibular gland was seen in any of the case. Preservation of submandibular glands can be a good technique for reducing future complications in a patient undergoing Neck Dissection wherever feasible. Therefore, if there is no need to expose large oral cavity tumors through the submandibular triangle, or when there is no direct extension of the primary and/or regional lymph nodes into the submandibular gland, it may be safe to preserve the submandibular gland.

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References

  1. Kocher T (1880) Ueber radicalheilung des krebses. Dtsch Z Chir 13:134

    Article  Google Scholar 

  2. Crile G (1906) Excision of cancer of the head and neck. JAMA 47:1780–1786

    Article  Google Scholar 

  3. Martin H, Del Valle B, Ehrlich H et al (1951) Neck dissection. Cancer 4:441–499

    Article  CAS  PubMed  Google Scholar 

  4. Bergonie J (1911) Sur quelques formes de reactions precoces apres des irradiations. Arch Elect Med 19:241–245

    Google Scholar 

  5. Murdoch-Kinch CA, Kim HM, Vineberg KA et al (2008) Dose-effect relationships for the submandibular salivary glands and implications for their sparing by intensity modulated radiotherapy. Int J Radiat Oncol Biol Phys 72:373–382

    Article  PubMed  PubMed Central  Google Scholar 

  6. Jacob RF, Weber RS, King GE (1996) Whole salivary flow rates following submandibular gland resection. Head Neck 18:242–247

    Article  CAS  PubMed  Google Scholar 

  7. DiNardo LJ (1998) Lymphatics of the submandibular space: an anatomic, clinical, and pathologic study with applications to floor of mouth carcinoma. Laryngoscope 108:206–214

    Article  CAS  PubMed  Google Scholar 

  8. Rinaldo A, Robbins KT, Ferlito A (2004) The importance of distinguishing between sublevel IA and IB in neck dissection. ORL 66:53–55

    Article  PubMed  Google Scholar 

  9. Rosti G, Callea A, Merendi R, Beccati D, Tienqhi A, Turci D et al (1987) Metastasis to the submaxillary gland from breast cancer: case report. Tumori 73:413–416

    CAS  PubMed  Google Scholar 

  10. Vessecchia G, Di Palma S, Giardini R (1995) Submandibular gland metastasis of breast carcinoma; a case report and a review of the literature. Virchows Arch 427(3):349–351

    Article  CAS  PubMed  Google Scholar 

  11. Spiegel JH, Brys AK, Bhakti A, Singer MI (2004) Metastasis to the submandibular gland in head and neck carcinomas. Head Neck 26:1064–1068

    Article  PubMed  Google Scholar 

  12. Byeon HK, Lim YC, Koo BS, Choi EC (2009) Metastasis to the submandibular gland in oral cavity squamous cell carcinomas: pathologic analysis. Acta Otolaryngol 129:96–100

    Article  PubMed  Google Scholar 

  13. Razfar A, Walvekar RR, Melkane A, Johnson JT, Myers EN (2009) Incidence and patterns of regional metastasis in early oral squamous cell cancers: feasibility of submandibular gland preservation. Head Neck 31:1619–1623

    Article  PubMed  Google Scholar 

  14. Chen TC, Lo WC, Ko YJ, Lou PJ, Yang TL, Wang CP (2009) Rare involvement of submandibular gland by oral squamous cell carcinoma. Head Neck 31:877–881

    Article  PubMed  Google Scholar 

  15. Takes RP, Robbins KT, Woolgar JA, Rinaldo A, Silver CE, Olofsson J et al (2011) Questionable necessity to remove the submandibular gland in neck dissection. Head Neck 33(5):743–745

    Article  PubMed  Google Scholar 

  16. Ebrahim AK, Loock JW, Afrogheh A, Hille J (2011) Is it oncologically safe to leave the ipsilateral submandibular gland during neck dissection for head and neck squamous cell carcinoma? J Laryngol Otol 125(8):837–840

    Article  CAS  PubMed  Google Scholar 

  17. Woolgar JA, Triantafyllou A (2009) Pitfalls and procedures in the histopathological diagnosis of oral and oropharyngeal squamous cell carcinoma and a review of the role of pathology in prognosis. Oral Oncol 45:361–385

    Article  PubMed  Google Scholar 

  18. Evans RW, Cruickshank AH (1970) Epithelial tumors of the salivary glands. Major Probl Pathol 1:1–299

    CAS  PubMed  Google Scholar 

  19. Humphrey SP, Williamson RT (2001) A review of saliva: normal composition, flow, and function. J Prosthet Dent 85(2):162–169

    Article  CAS  PubMed  Google Scholar 

  20. Chambers MS, Rosenthal DI, Weber RS (2007) Radiation-induced xerostomia. Head Neck 29:58–63

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of ENT, MGIMS, Sevagram, District Wardha, Maharashtra, 442102, India

    Gaurav Agarwal, Prakash S. Nagpure & Sushil S. Chavan

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  1. Gaurav Agarwal
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  2. Prakash S. Nagpure
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  3. Sushil S. Chavan
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Correspondence to Gaurav Agarwal.

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Agarwal, G., Nagpure, P.S. & Chavan, S.S. Questionable Necessity for Removing Submandibular Gland in Neck Dissection in Squamous Cell Carcinoma of Oral Cavity. Indian J Otolaryngol Head Neck Surg 68, 314–316 (2016). https://doi.org/10.1007/s12070-016-0966-4

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  • DOI: https://doi.org/10.1007/s12070-016-0966-4

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