Skip to main content
SpringerLink
Log in

Comparative Study Between Double Layered Repair of Pharyngeal Mucosa Against Routine Single Layered Repair in Cases of “Total Laryngectomy with Partial Pharyngectomy” in Respect To Formation of Pharyngo-cutaneous Fistula

  • Original Article
  • Published:
Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

Advanced glottic cancer (T3,N+ & T4) is usually treated in the majority of centres by total laryngectomy. Carcinoma of the larynx is one of the very few subsets of all cancers which have shown a decrease in the 5 year survival rate and this phenomenon has been attributed to a Pharyngo-cutaneous fistula is the most common complication after total laryngectomy. Comparative study between double layered repair of pharyngeal mucosa against routine single layered repair in cases of “total laryngectomy with partial pharyngectomy”. All patients with the principal procedure of “total laryngectomy with partial pharyngectomy” in department of otorhinolaryngology and head-neck surgery, Netaji Subhash Chandra Bose Medical College, Jabalpur, Madhya Pradesh, India were included in this study. Out of the 20 patients who had undergone total laryngectomy irrespective of the type of mucosal repair, 5 (25 %) patients developed pharyngocutaneous fistula. Out of the 8 patients, with double layered mucosa repair, 1 (12.5 %) patient developed pharyngocutaneous fistula. Out of the 12 patients, with single layered mucosa repair, 4 (33 %) patients developed pharyngocutaneous fistula. Double layered repair of pharyngeal mucosa is associated with a lower incidence of pharyngocutaneous fistula formation and no increased incidence of dysphagia after complete radiotherapy as compared to single layered repair.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Cavalot AL, Gervasio CF, Nazionale G, Albera R, Bussi M, Staffieri A et al (2000) Pharyngocutaneous fistula as a complication of total laryngectomy: review of the literature and analysis of case records. Otolaryngol Head Neck Surg 123(5):587–592

    Article  CAS  PubMed  Google Scholar 

  2. Galli J, De Corso E, Volante M, Almadori G, Paludetti G (2005) Postlaryngectomy pharyngocutaneous fistula: incidence, predisposing factors, and therapy. Otolaryngol Head Neck Surg 133(5):689–694

    Article  PubMed  Google Scholar 

  3. Parikh SR, Irish JC, Curran AJ, Gullane PJ, Brown DH, Rotstein LE (1998) Pharyngocutaneous fistulae in laryngectomy patients: the Toronto Hospital experience. J Otolaryngol 27(3):136–140

    CAS  PubMed  Google Scholar 

  4. Tomkinson A, Shone GR, Dingle A, Roblin DG, Quine S (1996) Pharyngocutaneous fistula following total laryngectomy and post-operative vomiting. Clin Otolaryngol Allied Sci 21(4):369–370

    Article  CAS  PubMed  Google Scholar 

  5. Venegas MP, León X, Quer M, Matiño E, Montoro V, Burgués J (1997) Complications of total laryngectomy in relation to the previous radiotherapy. Acta Otorrinolaringol Esp 48(8):639–646

    CAS  PubMed  Google Scholar 

  6. Markou KD, Vlachtsis KC, Nikolaou AC, Petridis DG, Kouloulas AI, Daniilidis IC (2004) Incidence and predisposing factors of pharyngocutaneous fistula formation after total laryngectomy. Is there a relationship with tumor recurrence? Eur Arch Otorhinolaryngol 261(2):61–67

    Article  PubMed  Google Scholar 

  7. Bresson K, Rasmussen H, Rasmussen PA (1974) Pharyngo-cutaneous fistulae in totally laryngectomized patients. J Laryngol Otol 88(9):835–842

    Article  CAS  PubMed  Google Scholar 

  8. Thawley SE (1981) Complications of combined radiation therapy and surgery for carcinoma of the larynx and inferior hypopharynx. Laryngoscope 91(5):677–700

    CAS  PubMed  Google Scholar 

  9. Virtaniemi JA, Kumpulainen EJ, Hirvikoski PP, Johansson RT, Kosma VM (2001) The incidence and etiology of postlaryngectomy pharyngocutaneous fistulae. Head Neck 23(1):29–33

    Article  CAS  Google Scholar 

  10. Weber RS, Berkey BA, Forastiere A et al (2003) Outcome of salvage total laryngectomy following organ preservation therapy: the radiation therapy oncology group trial 91–11. J Arch Otolaryngol Head Neck Surg 129:44

    Article  Google Scholar 

  11. Sessions DG, Ogura JH, Fried MP (1975) Carcinoma of the subglottic area. Laryngoscope 85:1417

    Article  CAS  PubMed  Google Scholar 

  12. Thawley SE (1981) Complications of combined radiation therapy and surgery for carcinoma of the larynx and inferior hypopharynx. Laryngoscope 41:677

    Google Scholar 

  13. Grau C, Johansen LV, Hansen HS (2003) Salvage laryngectomy and pharyngocutaneous fistulae after primary radiotherapy for head and neck cancer: a national survey from DAHANCA. Head Neck 25:711

    Article  PubMed  Google Scholar 

  14. Virtaniemi JA et al (2001) The incidence and etiology of postlaryngectomy pharyngocutaneous fistulae. Head Neck 23:29

    Article  CAS  Google Scholar 

  15. Ganly I, Patel S, Matsuo J et al (2005) Postoperative complications of salvage total laryngectomy. Cancer 15:2073–2078

    Article  Google Scholar 

  16. Schwarts SR, Yueh B, Maynard C et al (2004) Predictors of wound complications after laryngectomy: a study of over 2000 patients. Otolaryngol Head Neck Surg 131:61–68

    Article  Google Scholar 

  17. Mario A. Landera, Donna S. Lundy, Paula A. Sullivan: Dysphagia After Total Laryngectomy. Journals.asha 2010; 40–44

Download references

Author information

Author notes

  1. Vivek Dudeja

    Present address: , H.No. 1336, Sector-13, Near Community Centre, Hisar, Haryana, 125005, India

Authors and Affiliations

  1. Department of Otorhinolaryngology and Head Neck Surgery, Netaji Subhash Chandra Bose Medical College and Hospital, Jabalpur, India

    Anirudh Shukla & Vivek Dudeja

  2. H.No. 1349, Home Science College Road, Napier Town, Jabalpur, 482002, Madhya Pradesh, India

    Anirudh Shukla

  3. H.No. 104, H.I.G Dhanwantry Nagar, Near Medical College, Jabalpur, Madhya Pradesh, India

    Vivek Dudeja

Authors
  1. Anirudh Shukla
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Vivek Dudeja
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Vivek Dudeja.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Shukla, A., Dudeja, V. Comparative Study Between Double Layered Repair of Pharyngeal Mucosa Against Routine Single Layered Repair in Cases of “Total Laryngectomy with Partial Pharyngectomy” in Respect To Formation of Pharyngo-cutaneous Fistula. Indian J Otolaryngol Head Neck Surg 67 (Suppl 1), 8–11 (2015). https://doi.org/10.1007/s12070-014-0704-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12070-014-0704-8

Keywords

Search

Navigation