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Advances in Nano Biotic/Abiotic Hybrid Systems: Protein-Based Engineered Devices

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NanoBiotechnology

Abstract

Integrative nanobiotechnology utilizes natural ideas and materials for manufacturing nanoscale devices. As living organisms traditionally represent a good model for engineers to learn from, biological components of interest, with optimal functionality, have been used in the creation of biotic/abiotic hybrid devices. As an example, bacteriorhodopsin/F0F1-ATP-synthase-incorporated polymer vesicles provide a model of hybrid protein/artificial synthetic membrane system to perform biological functions. Some potential applications are the construction of intervesicular/intravesicular communications, such as excitable vesicles (EVs), for biocomputer and biomolecular motor-powered nanoelectromechanical systems (NEMS) for nanomedicine. Finally, advanced biotic/abiotic hybrid technology is expected to provide an alternative method to conventional fabrication technology to meet the increasing demands by saving enormous engineering efforts.

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Acknowledgements

The authors thank Jeffrey Germain for useful discussions.

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Authors and Affiliations

  1. Department of Biomedical Engineering, University of Cincinnati, 2901 Woodside Drive, ML 0048, Cincinnati, OH, 45221, USA

    Hyo-Jick Choi, David Wendell & Carlo D. Montemagno

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  1. Hyo-Jick Choi
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  2. David Wendell
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  3. Carlo D. Montemagno
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Correspondence to Carlo D. Montemagno.

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Choi, HJ., Wendell, D. & Montemagno, C.D. Advances in Nano Biotic/Abiotic Hybrid Systems: Protein-Based Engineered Devices. Nanobiotechnol 3, 66–75 (2007). https://doi.org/10.1007/s12030-008-9008-y

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  • DOI: https://doi.org/10.1007/s12030-008-9008-y

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