, Volume 43, Issue 1, pp 133-136
Date: 19 Oct 2010

Gastric Adenocarcinoma? Looks Similar but Behaves Differently!

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Case Presentation

A 63-year-old male presented with unintentional weight loss of 20 lb over a 4-month duration. He reported loss of appetite, intermittent post-prandial nausea, bloating, and early satiety. The patient also complained of dyspepsia and had been empirically treated for reflux disease during the previous 2 years. He denied vomiting, dysphagia, odynophagia, or abdominal pain. There was no history of overt gastrointestinal bleeding or alterations in bowel habits. Additionally, he denied fevers, night sweats, cough, or dyspnea. He had quit smoking 25 years ago, and denied alcohol use. His past medical history was significant for basal cell carcinoma treated with local curative therapy and he was without recurrence on surveillance. Pertinent family history included a paternal uncle with lung cancer at the age of 74. Physical examination was unremarkable except for occult heme-positive stools. Laboratory evaluation revealed elevated liver enzymes (ALT—112 U/L, reference range, 7