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Mirizzi syndrome is an important complication of gallstone disease. If not recognized preoperatively, it can result in significant morbidity and mortality. Preoperative diagnosis may be difficult despite the availability of multiple imaging modalities. Ul-trasonography (US), CT, and magnetic resonance cholangiopancreatography (MRCP) are common initial tests for suspected Mirizzi syndrome. Typical findings on US suggestive of Mirizzi syndrome are a shrunken gallbladder, impacted stone(s) in the cystic duct, a dilated intrahepatic tree, and common hepatic duct with a normal-sized common bile duct. The main role of CT is to differentiate Mirizzi syndrome from a malignancy in the area of porta hepatis or in the liver. MRI and MRCP are increasingly playing an important role and have the additional advantage of showing the extent of inflammation around the gallbladder that can help in the differentiation of Mirizzi syndrome from other gallbladder pathologies such as gallbladder malignancy. Endoscopic retrograde cholangiopancreatography (ERCP) is the gold standard in the diagnosis of Mirizzi syndrome. It delineates the cause, level, and extent of biliary obstruction, as well as ductal abnormalities, including fistula. ERCP also offers a variety of therapeutic options, such as stone extraction and biliary stent placement. Percutaneous cholangiogram can provide information similar to ERCP; however, ERCP has an additional advantage of identifying a low-lying cystic duct that may be missed on percutaneous cholangiogram. Wire-guided intraductal US can provide high-resolution images of the biliary tract and adjacent structures. Treatment is primarily surgical. Open surgery is the current standard for managing patients with Mirizzi syndrome. Good short-and long-term results with low mortality and morbidity have been reported with open surgical management. Laparoscopic management is contraindicated in many patients because of the increased risk of morbidity and mortality associated with this approach. Endoscopic treatment may serve as an alternative in patients who are poor surgical candidates, such as elderly patients or those with multiple comorbidities. Endoscopic treatment also can serve as a temporizing measure to provide biliary drainage in preparation for an elective surgery.
- Everhart JE, Khare M, Hill M, et al.: Prevalence and ethnic differences in gallbladder disease in the United States. Gastroenterology 1999, 117:632–639. CrossRef
- Mirizzi PL: Sindrome del conducto hepatico [in Italian]. J Int Chir 1948, 8:731–777.
- Puestow CB: Spontaneous internal biliary fistula. Ann Surg 1942, 115:1043–1054. CrossRef
- Corlette MB, Bismuth H: Biliobiliary fistula. A trap in the surgery of cholelithiasis. Arch Surg 1975, 110:377–383.
- Morelli A, Narducci F, Ciccone R: Can Mirizzi syndrome be classified into acute and chronic form? An endoscopic retrograde cholangiography (ERC) study. Endoscopy 1978, 10:109–112.
- Nagakawa T, Ohta T, Kayahara M, et al.: A new classification of Mirizzi syndrome from diagnostic and therapeutic viewpoints. Hepatogastroenterology 1997, 44:63–67.
- McSherry CK, Ferstenberg H, Virship M: The Mirizzi syndrome: suggested classification and surgical therapy. Surg Gastroenterol 1982, 1:219–225.
- Csendes A, Diaz JC, Burdiles P, et al.: Mirizzi syndrome and cholecystobiliary fistula: a unifying classification. Br J Surg 1989, 76:1139–1143. CrossRef
- Yip AW, Chow WC, Chan J, et al.: Mirizzi syndrome with cholecystocholedochal fistula: preoperative diagnosis and management. Surgery 1992, 111:335–338.
- Abou-Saif A, Al-Kawas FH: Complications of gallstone disease: Mirizzi syndrome, cholecystocholedochal fistula, and gallstone ileus. Am J Gastroenterol 2002, 97:249–254. CrossRef
- Curet MJ, Rosendale DE, Congilosi S: Mirizzi syndrome in a Native American population. Am J Surg 1994, 168:616–621. CrossRef
- England RE, Martin DF: Endoscopic management of Mirizzi’s syndrome. Gut 1997, 40:272–276.
- Guzan-Valdivia G: Xanthogranulomatous cholecystitis: 15 years’ experience. World J Surg 2004, 28:254–257. CrossRef
- Principe A, Del Gaudio M, Grazi GL, et al.: Mirizzi syndrome with cholecysto-choledochal fistula with a high CA 199 level mimicking biliary malignancies: a case report. Hepatogastroenterology 2003, 50:1259–1262.
- Nishimura A, Shirai Y, Hatakeyama K: High coincidence of Mirizzi syndrome and gallbladder carcinoma. Surgery 1999, 126:587–588. CrossRef
- Becker CD, Hassler H, Terrier F: Preoperative diagnosis of the Mirizzi syndrome: limitations of sonography and computed tomography. AJR Am J Roentgenol 1984, 143:591–596.
- Tan KY, Ching HC, Chen CY, et al.: Mirizzi syndrome: noteworthy aspects of a retrospective study in one centre. ANZ J Surg 2004, 74:833–837. CrossRef
- Ibrarullah MD, Saxena R, Sikora SS, et al.: Mirizzi’s syndrome: identification and management strategy. Aust N Z J Surg 1993, 63:802–806. CrossRef
- Johnson LW, Sehon JK, Lee WC, et al.: Mirizzi’s syndrome: experience from a multi-institutional review. Am Surg 2001, 67:11–14.
- Xiaodong H, Hongsheng L, Chaoji Z, et al.: Diagnosis and treatment of the Mirizzi syndrome. Chin Med Sci J 1999, 14:246–248.
- Kaya D, Karcaaltincaba M, Akhan O, et al.: MRCP diagnosis of Mirizzi syndrome in a paediatric patient: importance of T1-weighted gradient echo images for diagnosis. Pediatr Radiol 2006, 36:980–982. CrossRef
- Kim PN, Outwater EK, Mitchell DG: Mirizzi syndrome: evaluation by MRI imaging. Am J Gastroenterol 1999, 94:2546–2550. CrossRef
- Cornud F, Grenier P, Belghiti J, et al.: Mirizzi syndrome and biliobiliary fistulas: roentgenologic appearance. Gastrointest Radiol 1981, 6:265–268. CrossRef
- Ravo B, Epstein H, La Mendola S, et al.: The Mirizzi syndrome: preoperative diagnosis by sonography and transhepatic cholangiography. Am J Gastroenterol 1986, 81:688–690.
- Cruz FO, Barriga P, Tocornal J, et al.: Radiology of the Mirizzi syndrome: diagnostic importance of the transhepatic cholangiogram. Gastrointest Radiol 1983, 8:249–253. CrossRef
- Wehrmann T, Riphaus A, Martchenko K, et al.: Intraductal ultrasonography in the diagnosis of Mirizzi syndrome. Endoscopy 2006, 38:717–722. CrossRef
- Moon JH, Cho YD, Cheon YK, et al.: Wire-guided intraductal US in the assessment of bile duct strictures with Mirizzi syndrome-like features at ERCP. Gastrointest Endosc 2002, 56:873–879. CrossRef
- Baer HU, Matthews JB, Schweizer WP, et al.: Management of the Mirizzi syndrome and the surgical implication of cholecystocholedochal fistula. Br J Surg 1990, 77:743–745. CrossRef
- Venkatesh Rao PS, Tandon RK, Kapur BM: Biliobiliary fistula: review of nine cases. Am J Gastroenterol 1988, 83:652–657.
- Tranter SE, Thompson MH: Potential of laparoscopic ultrasonography as an alternative to operative cholangiography in the detection of bile duct stones. Br J Surg 2001, 88:65–69. CrossRef
- Meng WC, Kwok SP, Kelly SB, et al.: Management of Mirizzi syndrome by laparoscopic cholecystectomy and laparoscopic ultrasonography. Br J Surg 1995, 82:396. CrossRef
- Khan TF, Muniandy S, Hayat FZ, et al.: Mirizzi syndrome: a report of 3 cases with a review of the present classifications. Singapore Med J 1999, 40:171–173.
- Douglas PR, Ham JM: Partial cholecystectomy. Aust N Z J Surg 1990, 60:595–597. CrossRef
- Katsohis C, Prousalidis J, Tzardinoglou E, et al.: Subtotal cholecystectomy. HPB Surg 1996, 9:133–136. CrossRef
- Sandblom P, Tabrizian M, Rigo M, et al.: Repair of common bile duct defects using the gallbladder or cystic duct as a pedicled graft. Surg Gynecol Obstet 1975, 140:425–432.
- Strugnell NA, Sali A: Choledochoplasty for cholecystocholedochal fistula (Mirizzi syndrome type II): a case report and literature review. Aust N Z J Surg 1995, 65:285–288. CrossRef
- Binmoeller KF, Thonke F, Soehendra N: Endoscopic treatment of Mirizzi’s syndrome. Gastrointest Endosc 1993, 39:532–536.
- Tsuyuguchi T, Saisho H, Ishihara T, et al.: Long-term follow-up after treatment of Mirizzi syndrome by peroral cholangioscopy. Gastrointest Endosc 2000, 52:639–644. CrossRef
- Benninger J, Rabenstein T, Farnbacher M, et al.: Extracorporeal shockwave lithotripsy of gallstones in cystic duct remnants and Mirizzi syndrome. Gastrointest Endosc 2004, 60:454–459. CrossRef
- Cairns SR, Watson GN, Lees WR, et al.: Percutaneous lithotripsy and endoprosthesis: a new treatment for obstructive jaundice in Mirizzi’s syndrome. Br Med J 1987, 295:1448.
- Oxtoby JW, Yeong CC, West DJ: Mirizzi syndrome treated by percutaneous stone removal. Cardiovasc Intervent Radiol 1994, 17:207–209. CrossRef
- Adam A, Roddie ME, Benjamin IS: Case report: Mirizzi syndrome—treatment with metallic endoprosthesis. Clin Radiol 1993, 48:198–200. Discussion 200–201. CrossRef
- Contini S, Dalla Valle R, Zinicola R, et al.: Undiagnosed Mirizzi’s syndrome: a word of caution for laparoscopic surgeons—a report of three cases and review of the literature. J Laparoendosc Adv Surg Tech A 1999, 9:197–203.
- Chowbey PK, Sharama A, Khullar R, et al.: Laparoscopic subtotal cholecystectomy: a review of 56 procedures. J Laparoendosc Adv Surg Tech A 2000, 10:31–34.
- Mahmud S, Masaud M, Canna K, et al.: Fundus-first laparoscopic cholecystectomy. Surg Endosc 2002, 16:581–584. CrossRef
- Lai EC, Lau WY: Mirizzi syndrome: history, present and future development. ANZ J Surg 2006, 76:251–257. CrossRef
- Martin DF, Tweedle DE, Rao PN: Endoscopic gallbladder catheterization and extracorporeal shockwave lithotripsy in the management of Mirizzi syndrome. Endoscopy 1988, 20:321–322. CrossRef
- Delcenserie R, Joly JP, Dupas JL: Endoscopic diagnosis and treatment of Mirizzi syndrome. J Clin gastroenterol 1992, 15:343–346. CrossRef
- Vakil N, Sawyer R: Endoscopic drainage of the gallbladder in a septic variant of the Mirizzi syndrome. Gastrointest Endosc 1994, 40:236–238. CrossRef
- Hazzan D, Golijanin D, Reissman P, et al.: Combined endoscopic and surgical management of Mirizzi syndrome. Surg Endosc 1999, 13:618–620. CrossRef
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