Management of Recurrent Thrombosis in Antiphospholipid Syndrome
ANTIPHOSPHOLIPID SYNDROME (D ERKAN, SECTION EDITOR)
First Online: 22 January 2014 DOI:
10.1007/s11926-013-0405-4 Cite this article as: Nalli, C., Andreoli, L., Casu, C. et al. Curr Rheumatol Rep (2014) 16: 405. doi:10.1007/s11926-013-0405-4 Abstract
One of the challenges of managing patients with antiphospholipid syndrome is the prevention of rethrombosis (secondary prophylaxis). Risk stratification, i.e. traditional cardiovascular and thrombosis risk factors, systemic autoimmune diseases, antiphospholipid antibody profile, and the intensity of anticoagulation are all relevant to the management of APS patients with recurrent thrombosis. The paper will review “state of the art” strategies for optimizing therapy for APS patients with recurrent thrombosis.
Keywords Antiphospholipid antibodies Anticardiolipin antibodies Anti-β2glycoprotein I antibodies Lupus anticoagulant Thrombosis Recurrent thrombosis Stroke Primary antiphospholipid syndrome Cardiovascular risk factors Warfarin Low-dose aspirin Hydroxychloroquine Statins Heparin Rituximab Management
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