Current Osteoporosis Reports

, Volume 8, Issue 3, pp 118-122

First online:

Open Access This content is freely available online to anyone, anywhere at any time.

Timing of Subsequent Fractures after an Initial Fracture

  • Tineke A. C. M. van GeelAffiliated withDepartment of General Practice, Maastricht University/Caphri Email author 
  • , Kirsten M. B. HuntjensAffiliated withDepartment of General Surgery and Trauma Surgery, Maastricht University Medical Centre/Caphri
  • , Joop P. W. van den BerghAffiliated withDepartment of Internal Medicine, VieCuri Medical Centre Noord-LimburgDepartment of Internal Medicine, Maastricht University Medical Centre/Nutrim
  • , Geert-Jan DinantAffiliated withDepartment of General Practice, Maastricht University/Caphri
  • , Piet P. GeusensAffiliated withSubdivision Rheumatology, Department of Internal Medicine, Maastricht University Medical Centre/Caphri


A prior fracture is a well-documented risk factor for a subsequent fracture and it doubles the risk of subsequent fractures. Few studies have investigated the time that elapses between the initial and subsequent fracture. These studies show that the subsequent fracture risk is not constant, but fluctuates over time. The risk of subsequent vertebral, hip, and nonvertebral non-hip fractures is highest immediately after initial hip, clinical, and radiographic vertebral fractures and nonvertebral fractures and declines afterward, regardless of gender, age, and initial fracture location. These studies indicate the need for early action after an initial fracture with medical interventions that have an effect within a short term to reduce the preventable risks of subsequent fractures.


Osteoporosis Fractures Elderly