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Optimizing Quality and Efficiency of Healthcare Delivery in Hematopoietic Cell Transplantation

  • Health Economics (N Khera, Section Editor)
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Abstract

Hematopoietic cell transplantation is a complex and resource intense procedure that can be associated with high risks of treatment failure due to disease relapse or complications. There also exists considerable variability among transplant centers with respect to the number of procedures performed, available resources and personnel, patient selection, transplant practices, and supportive care. Hematopoietic cell transplantation as a specialty has been a pioneer in incorporating the constructs of quality and efficiency routinely in patient care. However, several challenges still remain. Harmonization of data collection and reporting, use of innovative technological tools, evidence-based practice supported by clinical trials, better efforts towards care coordination and transition of care, and reduction of variation will facilitate these efforts and will lead to improved experience and outcomes for hematopoietic cell transplant recipients.

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References

Papers of particular interest, published recently, have been highlighted as: •• Of major importance.

  1. Pasquini MC, Wang Z. Current use and outcome of hematopoietic stem cell transplantation: CIBMTR summary slides, 2013. Available at: http://www.cibmtr.org.

  2. Lee SJ, Astigarraga CC, Eapen M, et al. Variation in supportive care practices in hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2008;14(11):1231–8.

    Article  PubMed Central  PubMed  Google Scholar 

  3. Lee SJ, Joffe S, Artz AS, et al. Individual physician practice variation in hematopoietic cell transplantation. J Clin Oncol. 2008;26(13):2162–70.

    Article  PubMed  Google Scholar 

  4. Loberiza Jr FR, Zhang MJ, Lee SJ, et al. Association of transplant center and physician factors on mortality after hematopoietic stem cell transplantation in the United States. Blood. 2005;105(7):2979–87.

    Article  CAS  PubMed  Google Scholar 

  5. Majhail NS, Omondi NA, Denzen E, Murphy EA, Rizzo JD. Access to hematopoietic cell transplantation in the United States. Biol Blood Marrow Transplant. 2010;16(8):1070–5.

    Article  PubMed Central  PubMed  Google Scholar 

  6. Majhail NS, Mau LW, Chitphakdithai P, et al. National survey of hematopoietic cell transplantation center personnel, infrastructure, and models of care delivery. Biol Blood Marrow Transplant. 2015. Results of a national survey of US transplant centers that highlights the variation in resources available at transplant centers.

  7. Gratwohl A, Brand R, McGrath E, et al. Use of the quality management system "JACIE" and outcome after hematopoietic stem cell transplantation. Haematologica. 2014;99(5):908–15. Study that describes the association of survival with development of a quality management program for hematopoietic cell transplantation.

    Article  PubMed Central  PubMed  Google Scholar 

  8. Chabannon C, Pamphilon D, Vermylen C, et al. Ten years after the first inspection of a candidate European centre, an EBMT registry analysis suggests that clinical outcome is improved when hematopoietic SCT is performed in a JACIE accredited program. Bone Marrow Transplant. 2012;47(1):15–7.

    Article  CAS  PubMed  Google Scholar 

  9. Porter ME. What is value in health care? N Engl J Med. 2010;363(26):2477–81. Informative review on defining and implementing value in health care.

    Article  CAS  PubMed  Google Scholar 

  10. Logan BR, Nelson GO, Klein JP. Analyzing center specific outcomes in hematopoietic cell transplantation. Lifetime Data Anal. 2008;14(4):389–404.

    Article  PubMed Central  PubMed  Google Scholar 

  11. Center for International Blood and Marrow Transplant Research: U.S. transplant and survival statistics on related sites. http://www.cibmtr.org/ReferenceCenter/SlidesReports/USStats/Pages/index.aspx (Accessed March 23rd, 2015).

  12. Majhail NS, Nayyar S, Santibanez ME, Murphy EA, Denzen EM. Racial disparities in hematopoietic cell transplantation in the United States. Bone Marrow Transplant. 2012;47(11):1385–90.

    Article  CAS  PubMed  Google Scholar 

  13. Baker KS, Davies SM, Majhail NS, et al. Race and socioeconomic status influence outcomes of unrelated donor hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2009;15(12):1543–54.

    Article  PubMed Central  PubMed  Google Scholar 

  14. Joshua TV, Rizzo JD, Zhang MJ, et al. Access to hematopoietic stem cell transplantation: effect of race and sex. Cancer. 2010;116(14):3469–76.

    Article  PubMed Central  PubMed  Google Scholar 

  15. Denzen EM, Majhail NS, Stickney Ferguson S, et al. Hematopoietic cell transplantation in 2020: summary of year 2 recommendations of the National Marrow Donor Program’s System Capacity Initiative. Biol Blood Marrow Transplant. 2013;19(1):4–11.

    Article  PubMed Central  PubMed  Google Scholar 

  16. Majhail NS, Murphy EA, Denzen EM, et al. The National Marrow Donor Program’s Symposium on Hematopoietic Cell Transplantation in 2020: a health care resource and infrastructure assessment. Biol Blood Marrow Transplant. 2012;18(2):172–82.

    Article  PubMed  Google Scholar 

  17. Majhail NS, Murphy EA, Omondi NA, et al. Allogeneic transplant physician and center capacity in the United States. Biol Blood Marrow Transplant. 2011;17(7):956–61.

    Article  PubMed Central  PubMed  Google Scholar 

  18. Majhail NS, Jagasia M. Referral to transplant center for hematopoietic cell transplantation. Hematol Oncol Clin N Am. 2014;28(6):1201–13.

    Article  Google Scholar 

  19. Pidala J, Craig BM, Lee SJ, Majhail N, Quinn G, Anasetti C. Practice variation in physician referral for allogeneic hematopoietic cell transplantation. Bone Marrow Transplant. 2013;48(1):63–7.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  20. Majhail NS, Rizzo JD. Surviving the cure: long term follow-up of hematopoietic cell transplant recipients. Bone Marrow Transplant. 2013;48(9):1145–51.

    Article  CAS  PubMed  Google Scholar 

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Navneet Majhail declares no potential conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Correspondence to Navneet S Majhail.

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This article is part of the Topical Collection on Health Economics

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Majhail, N.S. Optimizing Quality and Efficiency of Healthcare Delivery in Hematopoietic Cell Transplantation. Curr Hematol Malig Rep 10, 199–204 (2015). https://doi.org/10.1007/s11899-015-0264-3

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  • DOI: https://doi.org/10.1007/s11899-015-0264-3

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