Nutrition and Obesity (S McClave, Section Editor)

Current Gastroenterology Reports

, Volume 14, Issue 4, pp 356-366

First online:

Nutrition Therapy Issues in Esophageal Cancer

  • Keith R. MillerAffiliated withDepartment of Surgery, University of Louisville Email author 
  • , Matthew C. BozemanAffiliated withDepartment of Surgery, University of Louisville

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access


Esophageal cancer has traditionally been a disease with poor long term outcomes in terms of both survival and quality of life. In combination with surgical and pharmacologic therapy, nutrition support has been demonstrated to improve patient tolerance of treatment, quality of life, and longterm outcomes. An aggressive multi-disciplinary approach is warranted with nutrition support remaining a cornerstone in management. Historically, nutrition support has focused on adequate caloric provision to prevent weight loss and allow for tolerance of treatment regimens. Alterations in metabolism occur in these patients making their use of available calories inefficient and the future of nutritional support may lie in the ability to alter this deranged metabolism. The purpose of this article is to review the current literature surrounding the etiology, treatment, and role of nutrition support in improving outcomes in esophageal cancer.


Nutrition therapy Esophageal cancer Malnutrition Nutritional screening Resectable disease Pharmacotherapy