Current Diabetes Reports

, Volume 5, Issue 4, pp 282–288

Oxidative stress: Changes in pregnancy and with gestational diabetes mellitus

Authors

  • Xinhua Chen
    • University of Medicine Science Center and Dentistry of New Jersey-SOM
  • Theresa O. Scholl
    • University of Medicine Science Center and Dentistry of New Jersey-SOM
Article

DOI: 10.1007/s11892-005-0024-1

Cite this article as:
Chen, X. & Scholl, T.O. Curr Diab Rep (2005) 5: 282. doi:10.1007/s11892-005-0024-1

Abstract

Pregnancy is susceptible to oxidative stress and antioxidant defenses can be altered in response to elevated levels of oxidative stress. Limited data in gestational diabetes mellitus (GDM) suggest that products of lipid peroxidation may be increased and antioxidant enzyme activities decreased, although the results have been inconsistent. As in type 2 diabetes mellitus (T2DM), glycemic levels in patients with GDM correlate with concentrations of lipid peroxides. The effects of supplementation with antioxidants or antioxidant-rich food in T2DM are controversial. Whether or not increased antioxidant intake can reduce the complications of GDM in both mother and fetus has not been explored.

Download to read the full article text

Copyright information

© Current Science Inc. 2005