ALLERGIC SKIN DISEASES (L FONACIER, SECTION EDITOR)

Current Allergy and Asthma Reports

, Volume 13, Issue 5, pp 518-527

Systemic Contact Dermatitis and Allergy to Biomedical Devices

  • Marcella AquinoAffiliated withSection of Allergy and Clinical Immunology, Winthrop-University HospitalRheumatology, Allergy & Immunology, Winthrop University Hospital Email author 
  • , Tania MucciAffiliated withSection of Allergy and Clinical Immunology, Winthrop-University HospitalRheumatology, Allergy & Immunology, Winthrop University Hospital

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Abstract

Systemic contact dermatitis (SCD) refers to a skin condition where an individual who is cutaneously sensitized to an allergen will subsequently react to that same allergen or a cross-reacting allergen via the systemic route. It occurs to allergens including metals, medications, and foods. There has been recent interest in metal allergy as it relates to the implantation of devices such as orthopedic, dental, cardiac, and gynecologic implants. This review will briefly address all causes of systemic contact dermatitis with a special and expanded focus on metal implant allergy. We present literature on SCD to various metal biomedical devices, patch testing for diagnosis of metal allergy pre and post implantation and treatment.

Keywords

Systemic contact dermatitis Allergic contact dermatitis Metal allergy Orthopedic implant Dental implant Dental amalgam Stent Pacemaker Intrauterine devices Biomedical devices