Current Allergy and Asthma Reports

, Volume 12, Issue 4, pp 339–345

Sesame Seed Food Allergy

FOOD ALLERGY (D ATKINS, SECTION EDITOR)

DOI: 10.1007/s11882-012-0267-2

Cite this article as:
Dalal, I., Goldberg, M. & Katz, Y. Curr Allergy Asthma Rep (2012) 12: 339. doi:10.1007/s11882-012-0267-2

Abstract

The number of reports regarding sesame seed food allergy (SFA) has increased significantly worldwide over the past two decades, either due to a genuine increase in SFA or merely an increase in its awareness. Its prevalence is difficult to estimate due to the lack of well designed prospective population-based studies. Based on the available data, we estimate that SFA affects 0.1–0.2 % of the population, in areas where the food is available. Albeit this prevalence appears to be relatively low, it is approximately one-half of that of persistent cow’s milk allergy. While only one fatality has been reported, the significant number of SFA patients presenting as anaphylaxis indicates the potential risk. Many reports based the diagnosis of SFA on sensitization criteria alone, particularly amongst atopic dermatitis patients. Elimination of sesame from the diet of these children utilizing such criteria is not justified, and may even increase the risk for developing SFA.

Keywords

Food allergySesame seedSPTSpecific IgEOral ChallengeAnaphylaxis

Abbreviations

AD

Atopic dermatitis

DBPCFC

Double blind placebo controlled food challenge

IgE

Immunoglobulin E

OC

Oral challenge

SFA

Sesame-seed food allergy

sIgE

Specific immunoglobulin E

SPT

Skin prick test

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Pediatric Allergy/Immunology Unit, E. Wolfson Medical Center, Sackler School of MedicineTel-Aviv UniversityHolonIsrael
  2. 2.The Institute of Allergy, Pulmonary and ImmunologyAssaf Harofeh Medical CenterZerifinIsrael