Abstract
Background
Metastatic tumours of the pancreas are rare and the optimal management of these tumours remains unclear, given the paucity of data existing in the literature. We report our experience of pancreatic metastasectomy.
Methods
Data were reviewed on all patients who underwent pancreatic resection for pathologically confirmed metastatic lesions over a consecutive 7-year period.
Results
Seven patients (two men and five women) underwent a pancreatectomy for a metastatic pancreatic tumour. The primary tumours were renal cell carcinoma (n = 3), colorectal carcinoma (n = 2) and leiomyosarcoma (n = 2). There was no operative mortality. Postoperative morbidities occurred in two patients. The median follow-up was 49 months (range 17–76). Overall 1- and 2-year survivals were 100 and 86 %, respectively, with a 2-year disease-free survival of 72 %.
Conclusions
Our series further supports that pancreatic metastasectomy can be performed safely and achieves acceptable survival outcomes.
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References
Adsay NV, Andea A, Basturk O et al (2004) Secondary tumors of the pancreas: an analysis of a surgical and autopsy database and review of the literature. Virchows Arch 444(6):527–535
Burke JP, Maguire D, Dillon J et al (2012) Whipple’s procedure for an oligometastasis to the pancreas from a leiomyosarcoma of the thigh. Ir J Med Sci 181(3):361–363
Untch BR, Allen PJ (2014) Pancreatic metastasectomy: the Memorial Sloan-Kettering experience and a review of the literature. J Surg Oncol 109(1):28–30
Mourra N, Arrive L, Balladur P et al (2010) Isolated metastatic tumors to the pancreas: Hopital St-Antoine experience. Pancreas 39(5):577–580
Jarufe N, McMaster P, Mayer AD et al (2005) Surgical treatment of metastases to the pancreas. Surgeon 3(2):79–83
Ghavamian R, Klein KA, Stephens DH et al (2000) Renal cell carcinoma metastatic to the pancreas: clinical and radiological features. Mayo Clin Proc 75(6):581–585
Adler H, Redmond CE, Heneghan HM et al (2014) Pancreatectomy for metastatic disease: a systematic review. Eur J Surg Oncol 40(4):379–386
Strobel O, Hackert T, Hartwig W et al (2009) Survival data justifies resection for pancreatic metastases. Ann Surg Oncol 16(12):3340–3349
Atiq M, Bhutani MS, Ross WA et al (2013) Role of endoscopic ultrasonography in evaluation of metastatic lesions to the pancreas: a tertiary cancer center experience. Pancreas 42(3):516–523
El Hajj II, LeBlanc JK, Sherman S, Al-Haddad MA, Cote GA, McHenry L et al (2013) Endoscopic ultrasound-guided biopsy of pancreatic metastases: a large single-center experience. Pancreas 42(3):524–530
Schnelldorfer T, Ware AL, Sarr MG et al (2008) Long-term survival after pancreatoduodenectomy for pancreatic adenocarcinoma: is cure possible? Ann Surg 247(3):456–462
Treasure T, Milosevic M, Fiorentino F et al (2014) Pulmonary metastasectomy: what is the practice and where is the evidence for effectiveness? Thorax. doi:10.1136/thoraxjnl-2013-204528
Aubin J-M, Rekman J, Vandenbroucke-Menu F et al (2013) Systematic review and meta-analysis of liver resection for metastatic melanoma. Br J Surg 100(9):1138–1147
Treasure T, Fallowfield L, Lees B et al (2012) Pulmonary metastasectomy in colorectal cancer: the PulMiCC trial. Thorax 67(2):185–187
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Redmond, C.E., Adler, H., Heneghan, H.M. et al. Pancreatic metastasectomy: experience of the Irish National Surgical Centre for Pancreatic Cancer. Ir J Med Sci 183, 677–680 (2014). https://doi.org/10.1007/s11845-014-1175-3
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DOI: https://doi.org/10.1007/s11845-014-1175-3