Abstract
The Growing Up in Ireland Infant Cohort dataset (n = 11,134) includes information on fertility treatments for over 400 infants. IVF (28.1 %) and IVF-related treatments (17.8 %) were the most frequent, but there was also a high percentage following clomiphene citrate alone (31.5 %). Infants born following fertility treatment were much more likely to be in higher income families, and this relationship was not accounted for by older mothers in wealthier families. Analysis of fertility-treatment pregnancies among Irish infants, controlling for income and maternal age, shows a greater risk of multiple birth and low birth-weight, although the latter appears to be largely related to the former especially for IVF-type treatments.
Notes
These 442 pregnancies are the basis of subsequent analyses in respect of fertility treatments, i.e. one infant per pregnancy. The twin children relating to the same birth event are excluded for all pregnancies (fertility and non-fertility treatments).
95 % confidence intervals throughout.
References
Nyboe Andersen A, Goossens V, Ferraretti AP et al (2008) Assisted reproductive technology in Europe, 2004: results generated from European Registers by ESHRE. Hum Reprod 23(4):756–771
de Mouzon J, Goossens V, Bhattacharya S et al (2010) Assisted reproductive technology in Europe, 2006: results generated from European Registers by ESHRE. Hum Reprod 25(8):1851–1862
de Mouzon J, Goossens V, Bhattacharya S et al (2012) Assisted reproductive technology in Europe, 2007: results generated from European Registers by ESHRE. Hum Reprod 27(4):954–966
Ferraretti AP, Goossens V, de Mouzon J et al (2012) Assisted reproductive technology in Europe, 2008: results generated from European Registers by ESHRE. Hum Reprod 27(9):2571–2584
Basit I, Johnson S, Mocanu E et al (2010) Mode of conception of triplets and high order multiple pregnancy in Dublin—a 10-year review (Poster Presentation Abstract). Arch Dis Child Fetal Neonatal 95:Fa53. doi:10.1136/adc.2010.189753.67
Allen C, Bowdin S, Harrison RF et al (2008) Pregnancy and perinatal outcomes after assisted reproduction: a comparative study. Ir J Med Sci 177:233–241
Human Fertilisation & Embryology Authority. (2006). Multiple pregnancies and births: considering the risks. Available online at http://www.hfea.gov.uk/cps/rde/xbcr/SID-3F57D79B-CC25CD59/hfea/multiple_births_final_Nov06.pdf. Accessed Nov 2011
Ashdown-Lambert JR (2005) A review of low birth weight: predictors, precursors and morbidity outcomes. JRSH 125(2):76–83
Aylward GP (2005) Neurodevelopmental outcomes of infants born prematurely. JDBP 26(6):427–440
Health Research and Information Division. (2010). Perinatal Statistics Report 2008 Available from http://www.esri.ie/health_information/nprs/nprs_reports/NPRS_AR_2008.pdf. Accessed July 2013
Quail A, Williams J, McCrory C, Murray A, Thornton M (2011) Sample Design and Response in Wave 1 of the Infant Cohort (at 9 Months) of Growing Up in Ireland. Available from http://www.ucd.ie/t4cms/GUI-SampleDesignResponseInfants.pdf
Quail A, Williams J, McCrory C, Murray A, Thornton M (2011) A Summary Guide to Wave 1 of the Infant Cohort (at 9 months) of Growing Up in Ireland. Available from http://www.ucd.ie/issda/static/documentation/esri/GUI-SummaryGuideInfants.pdf
Acknowledgments
Growing Up in Ireland data have been funded by the Government of Ireland through the Department of Children and Youth Affairs; and have been collected under the Statistics Act, 1993, of the Central Statistics Office. The project has been designed and implemented by the joint ESRI-TCD Growing Up in Ireland Study Team. The author wishes to thank the participating families and colleagues on the GUI Study Team, in particular Prof. James Williams.
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Murray, A. Biological risk versus socio-economic advantage: low birth-weight, multiple births and income variations among Irish infants born following fertility treatments. Ir J Med Sci 183, 667–670 (2014). https://doi.org/10.1007/s11845-014-1134-z
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DOI: https://doi.org/10.1007/s11845-014-1134-z