Skip to main content
Log in

Adverse childhood experiences, breast cancer, and psychotherapy

Expériences de vie précoces traumatiques, cancer du sein et psychothérapie

  • Original Article / Article Original
  • Published:
Psycho-Oncologie

Abstract

This study is based on 14 women’s breast cancer autobiographies that mention adverse childhood experiences. Recent research has established that early trauma tends to be associated with long-lasting physiological deregulations such as an overactive fight-or-flight response and a weakened immune competence. Stress hormones, such as cortisol, play a crucial role in tumor genesis, therefore, a relationship between adverse childhood events and breast cancer can be hypothesized. However, successful psychotherapy combining a somatic technique and a talking cure can reverse the harmful effects of early adverse experiences through the epigenetic route.

Résumé

Cette étude est fondée sur 14 récits autobiographiques de femmes ayant un cancer du sein. Ces dernières mentionnent des expériences de vie précoces traumatiques. Des recherches récentes ont établi que les traumas précoces tendent à être associés à des dérégulations durables telles qu’une hyperactivité du système attaque–fuite et un affaiblissement des compétences immunitaires. Les hormones du stress telles le cortisol jouent un rôle crucial dans la genèse des tumeurs, par conséquent, on peut faire l’hypothèse d’un lien entre les événements de vie précoces traumatiques et le cancer du sein. Toutefois, le recours à des interventions psychothérapeutiques, associant technique corporelle et cure par la parole, pourrait potentiellement neutraliser les effets néfastes des traumas précoces par la voie épigénétique.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Références

  1. Ogden P (2009) Emotion, mindfulness, and movement. In: Fosha D, Siegel D, Solomon M (eds) The healing power of emotions, affective neuroscience, development, and clinical practice. Norton, New York, NY

    Google Scholar 

  2. Ford JD (2010) Complex adult sequelae of early life exposure to psychological trauma. In: Lanius RA, Vermetten E, Pain C (dir) The impact of early life trauma on health and disease, the hidden epidemic. Cambridge University Press, Cambridge

    Google Scholar 

  3. La Prairie JL, Heim CM, Nemeroff CB (2010) The Neuroendocrine effects of early life trauma. In: Lanius RA, Vermetten E, Pain C (dir) The impact of early life trauma on health and disease, the hidden epidemic. Cambridge University Press, Cambridge

    Google Scholar 

  4. Felitti VJ, Anda RF (2010) The relationship of adverse childhood experiences, adult medical disease, psychiatric disorders, and sexual behavior: implications for healthcare. In: Lanius RA, Vermetten E, Pain C (dir) The impact of early life trauma on health and disease, the hidden epidemic. Cambridge University Press, Cambridge

    Google Scholar 

  5. Panksepp J (2009) Brain, emotional systems and qualities of mental life. In: Fosha D, Siegel D, Solomon M (eds) The healing power of emotions, affective neuroscience, development, and clinical practice. Norton, New York, NY

    Google Scholar 

  6. Schore A (2003) Affect regulation and the repair of the self. Norton, New York, NY

    Google Scholar 

  7. Tronick E (2009) Multilevel meaning making and dyadic expansion of consciousness theory. In: Fosha D, Siegel D, Solomon M (eds) The healing power of emotions, affective neuroscience, development, and clinical practice. Norton, New York, NY

    Google Scholar 

  8. Teicher MH, Rabi K, Sheu Y-S, et al (2010) Neurobiology of childhood trauma and adversity. In: Lanius RA, Vermetten E, Pain C (dir) The impact of early life trauma on health and disease, the hidden epidemic. Cambridge University Press, Cambridge

    Google Scholar 

  9. Chartier MJ, Walker JR, Naimark B (2007) Childhood abuse, adult health, and health care utilization: results from a representative community sample. Am J Epidemiol 165:1033–8

    Article  Google Scholar 

  10. Feinstein D, Church D (2010) Gene expression through psychotherapy: the contribution of non-invasive somatic interventions. Rev General Psychol 14:283–95

    Article  Google Scholar 

  11. Doidge N (2007) The brain that changes itself. Penguin, New York, NY

    Google Scholar 

  12. Maté G (2003) When the body says no, understanding the stressdisease connection. Wiley, Hoboken, NJ

    Google Scholar 

  13. Brown DW, Anda RF, Tiemeier H, et al (2009) Adverse childhood experiences and the risk of premature mortality. Am J Prev Med 37:389–96

    Article  PubMed  Google Scholar 

  14. Croner KR, Sachs-Ericsson N (2006) The association between child abuse, PTSD, and the occurrence of adult health problems: moderation via current life stress. J Trauma Stress 19:967–71

    Article  Google Scholar 

  15. Dong M, Dube SR, Felitti VJ, et al (2003) Adverse childhood experiences and self-reported liver disease. Arch Intern Med 163:1949–56

    Article  PubMed  Google Scholar 

  16. Francos A (1983) Sauve-toi, Lola. Ed Bernard Barrault, Paris

    Google Scholar 

  17. Kahane DH (1995) No less a woman: femininity, sexuality, and breast cancer. Hunter House Publishers, Boston, MA

    Google Scholar 

  18. Barasch MI (1995) The healing path. Penguin, New York, NY

    Google Scholar 

  19. Joseph B (1996) My healing from breast cancer. Heats Publishing, New Canaan, CT

    Google Scholar 

  20. McDougall J (2000) Theatres of the psyche. J Anal Psychol 45:45–64

    Article  PubMed  Google Scholar 

  21. Accad E (2001) The wounded breast. Spinifex, Melbourne

    Google Scholar 

  22. Bondar AB (2005) Messages from the heart: learning to love cancer. ThisIsMeAnnabelle Inc., Calgary, AB

    Google Scholar 

  23. Brunet C (2005) La Vie vaut mille maux. Editions de la Mortagne, Boucherville, QC

    Google Scholar 

  24. Rubert F (2006) La Vie est là, simplement. Albin Michel, Paris

    Google Scholar 

  25. Vaillant M (2008) Une année singulière avec mon cancer du sein. Albin Michel, Paris

    Google Scholar 

  26. Baker GK (2008) Cancer is a bitch. Da Capo Lifelong Books, Alameda, CA

    Google Scholar 

  27. Pettason A (2008) I am not my breast cancer. Harper, New York, NY

    Google Scholar 

  28. Tabet S (2010) Les Patientes. Les Empêcheurs de penser en rond, Paris

    Google Scholar 

  29. Gonzalez Pardo H, Alvarez M (2013) Epigenetics and its implications for psychology. Psicothema 25:3–12

    PubMed  Google Scholar 

  30. Thayer JF, Brosschot JF (2005) Psychosomatics and psychopathology, looking up and down from the brain. Psychoneuroendocrinology 30:1050–8

    Article  PubMed  Google Scholar 

  31. Justice B (1988) Who gets sick? St Martin’s Press, New York, NY

    Google Scholar 

  32. Pressman S, Cohen S (2005) Does positive affect influence health? Psychol Bull 133:925–71

  33. Antoni M (2013) Psychosocial intervention effects on adaptation, disease course and bio-behavioral processes in cancer. Brain Behav Immun 30:588–98

    Article  Google Scholar 

  34. Green Mc Donald P, O’Connell M, Lutgendorf S (2013) Psychoneuroimmunology: a decade of discovery, paradigm shifts, and methodological innovations. Brain Behav Immun 30:1–9

    Article  Google Scholar 

  35. Stankiewicz A, Swiergiel AH, Lisowski P (2013) Epigenetics of stress adaptation in the brain. Brain Res Bull 98:76–82

    Article  PubMed  Google Scholar 

  36. Miller G, Chen E, Cole SW (2009) Health psychology: developing biologically plausible models linking the social world and physical health. Annual Review of Psychology 60:501–24

    Article  PubMed  Google Scholar 

  37. Unternaehmer E, Luers P, Mill J, et al (2012) Dynamic changes in DNA methylation of stress-associated genes after acute psychosocial stress. Transl Psychiatry 2:50

    Google Scholar 

  38. Heinrichs M, Baumgartner T, Kirschbaum C, et al (2003) Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress. Biol Psychiatry 54:1389–98

    Article  PubMed  Google Scholar 

  39. Yahuda R, Bierer LM (2009) The relevance of epigenetics to PTSD: implications for the DSM5. J Trauma Stress 22:427–34

    Article  Google Scholar 

  40. Kelly-Irving M, Mabile L, Grosclaude P, et al (2013) The embodiment of adverse childhood experience and cancer development: potential biological mechanisms and pathways across the life course. Int J Public Health 58:3–11

    Article  PubMed  Google Scholar 

  41. Robles TF, Carroll JR (2011) Restorative biological processes and health. Soc Personal Psychol Compass 5:518–37

    Article  PubMed  PubMed Central  Google Scholar 

  42. Rodriguez T (2013) Clues about aging from chromosome caps: chronic pain and anxiety may prematurely age our DNA. Sci Am Mind 24:17

    Google Scholar 

  43. Ornish D, Lin J, Daubenmier J, et al (2008) Increased telomerase activity and comprehensive lifestyle changes: a pilot study. Lancet Oncol 9:1048–57

    Article  PubMed  Google Scholar 

  44. Matthews HL, Konley T, Kosik KL, et al (2011) Epigenetic patterns associated with immune dysregulation by psychological distress. Brain Behav Immun 25:830–9

    Article  Google Scholar 

  45. Gerhardt S (2004) Why love matters, how affection shapes a baby’s brain. Routledge, New York, NY

    Google Scholar 

  46. Fagundes CP, Glaser R, Kiecolt-Glaser JK (2013) Stressful early life experiences and immune dysregulation across the lifespan. Brain Behav Immun 27:8–12

    Article  PubMed  Google Scholar 

  47. Lewis CE, O’Sullivan C, Barraclough J (1994) The psychoneuroimmunology of cancer. Oxford University Press, Oxford

    Google Scholar 

  48. Kandel E (2005) Psychiatry, psychoanalysis and the new biology of the mind. American Psychiatric Publishing, Washington, DC

    Google Scholar 

  49. Siegel D (2009) Emotion as integration. In: Fosha D, Siegel D, Solomon M (eds) The healing power of emotions, affective neuroscience, development, and clinical practice. Norton, New York, NY

    Google Scholar 

  50. Brody H (2000) The placebo response. Harper Collins, New York, NY

    Google Scholar 

  51. Watkins A (1997) Mind-body medicine, a clinician’s guide to psycho-neuro-immunology. Churchill Livingstone, New York, NY

    Google Scholar 

  52. Fosha D (2009) Emotion and recognition at work. In: Fosha D, Siegel D, Solomon M (eds) The healing power of emotions, affective neuroscience, development, and clinical practice. Norton, New York, NY

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to C. -A. Wendling.

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Wendling, C.A. Adverse childhood experiences, breast cancer, and psychotherapy. Psycho Oncologie 10, 221–226 (2016). https://doi.org/10.1007/s11839-016-0588-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11839-016-0588-9

Keywords

Mots clés

Navigation