Lipids

, Volume 45, Issue 6, pp 501–510

Medium- and Long-Chain Triacylglycerols Reduce Body Fat and Blood Triacylglycerols in Hypertriacylglycerolemic, Overweight but not Obese, Chinese Individuals

  • Yuehong Zhang
  • Yinghua Liu
  • Jin Wang
  • Rongxin Zhang
  • Hongjiang Jing
  • Xiaoming Yu
  • Yong Zhang
  • Qin Xu
  • Jieying Zhang
  • Zixin Zheng
  • Naohisa Nosaka
  • Chie Arai
  • Michio Kasai
  • Toshiaki Aoyama
  • Jian Wu
  • Changyong Xue
Original Article

DOI: 10.1007/s11745-010-3418-z

Cite this article as:
Zhang, Y., Liu, Y., Wang, J. et al. Lipids (2010) 45: 501. doi:10.1007/s11745-010-3418-z

Abstract

In contrast to the consumption of long-chain triacylglycerols (LCT), consumption of medium- and long-chain triacylglycerols (MLCT) reduces the body fat and blood triacylglycerols (TAG) level in hypertriacylglycerolemic Chinese individuals. These responses may be affected by BMI because of obesity-induced insulin resistance. We aimed to compare the effects of consuming MLCT or LCT on reducing body fat and blood TAG level in hypertriacylglycerolemic Chinese subjects with different ranges of BMI. Employing a double-blind, randomized and controlled protocol, 101 hypertriacylglycerolemic subjects (including 67 men and 34 women) were randomly allocated to ingest 25–30 g/day MLCT or LCT oil as the only cooking oil for 8 consecutive weeks. Anthropometric measurements of body weight, BMI, body fat, WC, HC, blood biochemical variables, and subcutaneous fat area and visceral fat area in the abdomen were measured at week 0 and 8. As compared to subjects with BMI 24–28 kg/m2 in the LCT group, corresponding subjects in the MLCT group showed significantly greater decrease in body weight, BMI, body fat, WC, ratio of WC to HC, total fat area and subcutaneous fat area in the abdomen, as well as blood TAG and LDL-C levels at week 8. Based upon our results, consumption of MLCT oil may reduce body weight, body fat, and blood TAG and LDL-C levels in overweight hypertriacylglycerolemic Chinese subjects but may not induce these changes in normal or obese hypertriacylglycerolemic subjects.

Keywords

Medium-and long-chain triacylglycerolsBody fatBlood triacylglycerolsHypertriacylglycerolemiaOverweightChineseLong-chain triacylglycerols

Abbreviations

ALT

Alanine aminotransferase

AST

Aspartate aminotransferase

BMI

Body mass index

HC

Hip circumference

HDL-C

High-density lipoprotein-cholesterol

LCT

Long-chain triacylglycerols

LDL-C

Low-density lipoprotein-cholesterol

MLCT

Medium- and long-chain triacylglycerols

SFA

Subcutaneous fat area

TAG

Triacylglycerols

TFA

Total fat area

VFA

Visceral fat area

WC

Waist circumference

WHR

Ratio of waist circumference to hip circumference

Copyright information

© AOCS 2010

Authors and Affiliations

  • Yuehong Zhang
    • 1
  • Yinghua Liu
    • 1
  • Jin Wang
    • 1
  • Rongxin Zhang
    • 1
  • Hongjiang Jing
    • 1
  • Xiaoming Yu
    • 1
  • Yong Zhang
    • 1
  • Qin Xu
    • 1
  • Jieying Zhang
    • 1
  • Zixin Zheng
    • 1
  • Naohisa Nosaka
    • 2
  • Chie Arai
    • 2
  • Michio Kasai
    • 2
  • Toshiaki Aoyama
    • 2
  • Jian Wu
    • 2
  • Changyong Xue
    • 1
  1. 1.Department of NutritionChinese People’s Liberation Army General HospitalBeijingChina
  2. 2.Central Research LaboratoryNisshin Oillio GroupYokosukaJapan