A 45-year-old man developed chest and abdominal pain, vomiting, and right-sided weakness after an accidental ingestion. Upon arrival in the emergency department (ED), the chest pain and weakness had resolved, and vital signs were unremarkable. The patient had persistent abdominal pain and vomiting refractory to antiemetics. An abdominal CT scan was remarkable for severe esophagitis and gastritis, portal venous air, and pneumatosis of the stomach wall with concern for impending gastric rupture. Bedside ultrasound (US) was performed (Fig. 1a). A treatment was administered, and a repeat US was obtained (Fig. 1b).
The patient reported drinking approximately 100 mL of 35 % H2O2 that was in an unlabeled water bottle in his refrigerator. H2O2 is available in both dilute (3–9 %) and concentrated (27.5–70 %) forms. Higher concentration H2O2 is typically used in the commercial setting, but is now available in health food stores as “hyperoxygenation therapy.” Although small ingestions of dilute H2O2 typically cause only mild irritation, ingestions of higher concentrations H2O2 can result in significant caustic injury. In addition, each 1 mL 35 % H2O2 liberates approximately 100 mL oxygen upon interaction with tissue catalase, leading to a potential for air embolism and end organ ischemia even in accidental ingestions [1–3]. The use of H2O2 in closed spaces or under high pressure also transmits risk of embolization, and such complications have been reported after irrigation of surgical wounds with lower concentration (3 %) H2O2 [4, 5].
Hyperbaric oxygen therapy (HBOT) at 3 atmospheres was pursued. Thirty minutes prior to HBOT, bedside US demonstrated portal venous air (Fig. 1a). The pain resolved during HBOT, and repeat US 30 min after treatment showed resolution of portal venous air (Fig. 1b).
Indications for HBOT after H2O2 ingestion are not standardized. Though controversial, some recommend prophylactic HBOT for the presence of portal venous air [3]. In these cases, repeat CT imaging is often obtained to document resolution of air after HBOT, exposing patients to additional radiation. US may be an easy, radiation-free alternative to detect and show resolution of air in the cases of H2O2 ingestion.
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Spyres, M.B., Oakley, E. & Graeme, K.A. Ultrasound to evaluate effectiveness of hyperbaric oxygen therapy. Intern Emerg Med 12, 413–414 (2017). https://doi.org/10.1007/s11739-016-1513-8
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DOI: https://doi.org/10.1007/s11739-016-1513-8