Skip to main content
Log in

Données épidémiologiques sur la douleur du cancer en France. Évolution sur deux décennies de la prévalence et de l’intensité de la douleur chez les malades atteints de cancer

Epidemiologic data on cancer pain. Evolution of prevalence and intensity of pain in cancer patients during two decades in France

  • Article de Synthèse / Review Article
  • Published:
Douleur et Analgésie

Résumé

La douleur est fréquemment rencontrée en cancérologie, du fait de la maladie, du traitement de la maladie, ou d’une raison intercurrente. Ses mécanismes sont variés, elle peut être inflammatoire, neuropathique, somatique, viscérale, aiguë, chronique. Elle a un impact négatif sur la qualité de vie et potentiellement sur la survie. Son traitement fait appel à diverses approches, symptomatiques ou plus spécifiques. La prise en charge est fréquemment considérée comme peu satisfaisante, comme cela a été retrouvé en France. Quelques explications et propositions sont avancées.

Abstract

Pain is frequently encountered in patients with cancer, due to cancer itself, to cancer treatment, or to an independent cause. It is linked with various mechanisms as inflammatory, neuropathic, somatic or visceral, acute or chronic. It has a negative impact on patients’ quality of life, and probably on patients’ survival. Cancer pain treatment is based on the efficacy of various approaches such symptomatic or specific interventions. Cancer pain management is often considered as poor, as found in the results of French surveys. Some explanations and proposals are offered.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Références

  1. Bennett MJ (2012) Treatment of cancer pain. In: Tracey I Pain 2012. Refresher courses (14th World Congress on Pain). IASP Press, Seattle, pp 301–304

    Google Scholar 

  2. Bouhassira D, Attal N, Fermanian F, et al (2004) Development and validation of the Neuropathic Pain Symptom Inventory. Pain 108:248–257

    Article  PubMed  Google Scholar 

  3. Bouhassira D, Luporsi E, Krakowski I (2013) Prevalence and incidence of chronic pain with or without neuropathic characteristics in 1805 patients with cancer. Ann Oncol [in press]

    Google Scholar 

  4. Breuer B, Fleishman SB, Cruciani RA, et al (2011) Medical oncologists’ attitudes and practice in cancer pain management: a nationwide survey. J Clin Oncol 29:4769–4775

    Article  PubMed  Google Scholar 

  5. Caraceni A (2010) Are research and clinical practice improving management of pain in cancer patients? Why do patients still suffer? In: Paice JA, Bell RF, Kalso EA, Soyannwo OA eds (2010) Cancer pain. IASP Press, Seattle, pp 321–332

    Google Scholar 

  6. Caraceni A, Hanks G, Kaasa S, et al (2012) Use of opioid analgesics in the treatment of cancer pain: evidence-based recommendations from the EAPC. Lancet Oncol 13:e58–e68

    Article  PubMed  CAS  Google Scholar 

  7. Caraceni A, Portenoy RK, Ashby MA, et al (1999) An international survey of cancer pain characteristics and syndromes. Pain 82:263–274

    Article  PubMed  CAS  Google Scholar 

  8. Cherny NI, Baselga J, de Conno F, et al (2010) Formulary availability and regulatory barriers to accessibility of opioids for cancer pain in Europe: a report from the ESMO/EAPC Opioid Policy Initiative. Ann Oncol 21:615–626

    Article  PubMed  CAS  Google Scholar 

  9. Deandrea S, Montanari M, Moja L, Apolone G (2008) Prevalence of undertreatment in cancer pain. A review of published literature. Ann Oncol 19:1985–1991

    Article  PubMed  CAS  Google Scholar 

  10. Dworkin RH, O’Connor AB, Backonja M, et al (2007) Pharmacologic management of neuropathic pain: Evidence-based recommendations. Pain 132:237–251

    Article  PubMed  CAS  Google Scholar 

  11. Dworkin RH, Turk DC, Wyrwich KW, et al (2008) Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations. J Pain 9:105–121

    Article  PubMed  Google Scholar 

  12. Guirimand F, Buyck JF, Lauwers-Allot E, et al (2010) Cancer related symptom assessment in France: validation of the French M.D. Anderson Symptom Inventory. J Pain Symptom Manage 39:721–733

    Article  PubMed  Google Scholar 

  13. Gunnarsdottir S, Donovan HS, Serlin RC, et al (2002) Patientrelated barriers to pain management: the Barriers Questionnaire II (BQ-II). Pain 99:385–396

    Article  PubMed  Google Scholar 

  14. Hjermstad MJ, Fainsinger R, Kaasa S (2009) Assessment and classification of cancer pain. Current Opin Support Palliat Care 3:24–30

    Article  Google Scholar 

  15. Holtan A, Aass N, Nordoy T et al (2007) Prevalence of pain in hospitalised cancer patients in Norway: a national survey. Palliat Med 21:7–13

    Article  PubMed  Google Scholar 

  16. International Association for the Study of Pain (1979) Subcommittee on taxononomy of pain terms: a list with definitions and note on usage. Pain 6:249–252

    Google Scholar 

  17. Larue F, Colleau SM, Brasseur L, Cleeland CS (1995) Multicentre study of cancer pain and its treatment in France. BMJ 310:1034–1037

    Article  PubMed  CAS  Google Scholar 

  18. Larue F, Colleau SM, Fontaine A, Brasseur L (1995) Oncologists and primary care physicians’ attitudes towards pain control and morphine prescribing in France. Cancer 76:2375–2382

    Article  PubMed  CAS  Google Scholar 

  19. Larue F, Fontaine A, Brasseur L (1999) Evolution of the French public opinion on cancer pain and postoperative pain and their treatments: 2 national surveys over 6 years. Anesth Analg 89:659–664

    PubMed  CAS  Google Scholar 

  20. Last JM (1988) A dictionary of Epidemiology. Oxford University Press, New York

    Google Scholar 

  21. Oldenmenger WH, Sillevis Smitt PA, van Dooren S et al (2009) A systematic review on barriers hindering adequate cancer pain management and interventions to reduce them: a critical appraisal. Eur J Cancer 45:1370–1380

    Article  PubMed  Google Scholar 

  22. Patel S, Dickenson AH (2012) Mechanisms of cancer pain. In: Pain 2012, Refresher Courses 14 th World Congress on Pain (Tracey I ed), IASP Presse, Seattle: pp 293–296

    Google Scholar 

  23. Portenoy RK, Hagen NA (1990) Breakthrough pain: Definition, prevalence, and characteristics. Pain 41:273–281

    Article  PubMed  CAS  Google Scholar 

  24. Saunders CM (1985). The management of terminal illness. Arnold, London

    Google Scholar 

  25. Smith TJ, Staats PR, Deer T, et al (2002) Randomized clinical trial of an implantable drug delivery system compared with comprehensive management for refractory cancer pain: impact on pain, drug-related toxicity, and survival. J Clin Oncol 20:4040–4049

    Article  PubMed  CAS  Google Scholar 

  26. Synthèse de l’enquête nationale 2010 sur la prise en charge de la douleur chez des patients adultes atteints de cancer. INCa, mars 2012, www.e-cancer.fr

  27. Temel JS, Greer JA, Muzikansky A, et al (2010) Early palliative care for patients with metastatic non-small-cell lung cancer. N Engl J Med 363:733–742

    Article  PubMed  CAS  Google Scholar 

  28. van den Beuken-van Everdingen MH, de Rijke JM, Kessels AG, et al (2007) Prevalence of pain in patients with cancer: a systematic review of the past 40 years. Ann Oncol 18:1437–1449

    Article  PubMed  Google Scholar 

  29. Ventafridda V, Tamburini M, Caraceni A, et al (1987). A validation study of the WHO method for cancer pain management. Cancer 59:850–856

    Article  PubMed  CAS  Google Scholar 

  30. Walter C, Lotsch J (2009) Meta-analysis of the relevance of the OPRM1 118>G genetic variant for pain treatment. Pain 146:270–275

    Article  PubMed  CAS  Google Scholar 

  31. World Health Organization (1996) Cancer Pain Relief and Palliat ive Care, 2nd edition. World Health Organization, Geneva

    Google Scholar 

  32. Zenz M, Willweber-Strumpf A (1993) Opioiphobia and cancer pain in Europe. Lancet 341:1075–1076

    Article  PubMed  CAS  Google Scholar 

  33. Zigmond AS, Snaith RP (1983) The Hospital Anxiety and Depression Scale. Acta Psychiatr Scand 67:361–370

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to L. Brasseur.

About this article

Cite this article

Welsch, C., Delorme, T., Larue, F. et al. Données épidémiologiques sur la douleur du cancer en France. Évolution sur deux décennies de la prévalence et de l’intensité de la douleur chez les malades atteints de cancer. Douleur analg 26, 126–132 (2013). https://doi.org/10.1007/s11724-013-0345-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11724-013-0345-9

Mots clés

Keywords

Navigation