Brain Imaging and Behavior

, Volume 8, Issue 4, pp 621–634

Brain activation during neurocognitive testing using functional near-infrared spectroscopy in patients following concussion compared to healthy controls

  • A. P. Kontos
  • T. J. Huppert
  • N. H. Beluk
  • R. J. Elbin
  • L. C. Henry
  • J. French
  • S. M. Dakan
  • M. W. Collins
Original Research

DOI: 10.1007/s11682-014-9289-9

Cite this article as:
Kontos, A.P., Huppert, T.J., Beluk, N.H. et al. Brain Imaging and Behavior (2014) 8: 621. doi:10.1007/s11682-014-9289-9

Abstract

There is no accepted clinical imaging modality for concussion, and current imaging modalities including fMRI, DTI, and PET are expensive and inaccessible to most clinics/patients. Functional near-infrared spectroscopy (fNIRS) is a non-invasive, portable, and low-cost imaging modality that can measure brain activity. The purpose of this study was to compare brain activity as measured by fNIRS in concussed and age-matched controls during the performance of cognitive tasks from a computerized neurocognitive test battery. Participants included nine currently symptomatic patients aged 18–45 years with a recent (15–45 days) sport-related concussion and five age-matched healthy controls. The participants completed a computerized neurocognitive test battery while wearing the fNIRS unit. Our results demonstrated reduced brain activation in the concussed subject group during word memory, (spatial) design memory, digit-symbol substitution (symbol match), and working memory (X’s and O’s) tasks. Behavioral performance (percent-correct and reaction time respectively) was lower for concussed participants on the word memory, design memory, and symbol match tasks than controls. The results of this preliminary study suggest that fNIRS could be a useful, portable assessment tool to assess reduced brain activation and augment current approaches to assessment and management of patients following concussion.

Keywords

ConcussionMild Traumatic Brain InjuryNeurocognitive TestingNear Infrared Spectroscopy

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • A. P. Kontos
    • 1
    • 4
  • T. J. Huppert
    • 2
    • 3
  • N. H. Beluk
    • 2
  • R. J. Elbin
    • 1
  • L. C. Henry
    • 1
  • J. French
    • 1
  • S. M. Dakan
    • 1
  • M. W. Collins
    • 1
  1. 1.UPMC Sports Medicine Concussion Program/Department of Orthopaedic SurgeryUniversity of PittsburghPittsburghUSA
  2. 2.Department of RadiologyUniversity of PittsburghPittsburghUSA
  3. 3.Department of Biomedical EngineeringUniversity of PittsburghPittsburghUSA
  4. 4.UPMC Sports Medicine Concussion Program, Department of Orthopaedic SurgeryUniversity of Pittsburgh School of Medicine, UPMC Center for Sports MedicinePittsburghUSA