One-Pot Green Synthesis and Bioapplication of l -Arginine-Capped Superparamagnetic Fe3 O4 Nanoparticles
Water-soluble l-arginine-capped Fe3O4 nanoparticles were synthesized using a one-pot and green method. Nontoxic, renewable and inexpensive reagents including FeCl3, l-arginine, glycerol and water were chosen as raw materials. Fe3O4 nanoparticles show different dispersive states in acidic and alkaline solutions for the two distinct forms of surface binding l-arginine. Powder X-ray diffraction and X-ray photoelectron spectroscopy were used to identify the structure of Fe3O4 nanocrystals. The products behave like superparamagnetism at room temperature with saturation magnetization of 49.9 emu g−1 and negligible remanence or coercivity. In the presence of 1-ethyl-3-(dimethylaminopropyl) carbodiimide hydrochloride, the anti-chloramphenicol monoclonal antibodies were connected to the l-arginine-capped magnetite nanoparticles. The as-prepared conjugates could be used in immunomagnetic assay.
- One-Pot Green Synthesis and Bioapplication of l-Arginine-Capped Superparamagnetic Fe3O4 Nanoparticles
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Nanoscale Research Letters
Volume 5, Issue 2 , pp 302-307
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- 1. Key Laboratory for Colloid & Interface Chemistry of Education Ministry, Department of Chemistry, Shandong University, 250100, Jinan, People’s Republic of China
- 2. College of Pharmaceutical Sciences, Nankai University, 300071, Tianjin, People’s Republic of China