Abstract
Summary
The mean serum 25-OH-D was 23.1 ng/mL in 49 female Japanese college students, and concentrations in 33 % of them were ≤20 ng/mL. Subsequently, they consumed milk fortified with 2 μg of vitamin D daily for 8 weeks. Then, 25-OH-D increased to 36.0 ng/mL and all values were ≥20 ng/mL.
Purpose
Commercial milk in the USA is fortified with vitamin D (VD), whereas food fortified with VD is unpopular in Japan even though dietary sources of this vitamin are limited. Therefore, young Japanese females might be VD deficient. This study assesses the effects of ingesting milk fortified with VD among Japanese female college students.
Methods
Forty-nine female college students consumed 180 mL of milk fortified with 2 μg of VD daily for 8 weeks. This amount of VD in the milk was similar to that in commercial milk sold in the USA. Serum concentrations of 25-OH-D were measured in venous blood collected before and after the ingestion period.
Results
The initial serum 25-OH-D concentration was 23.1 ng/mL and concentrations in 33 % of the participants were ≤20 ng/mL. After 8 weeks, serum 25-OH-D increased to 36.0 ng/mL and all values were ≥20 ng/mL. Serum Ca and FGF-23 also increased and PTH, NTX, and BAP significantly decreased.
Conclusions
The high prevalence of VD deficiency in Japanese female college students was decreased by consuming VD-fortified milk.
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Acknowledgments
This study was funded partly by the Japan Dairy Association (J-milk). The fortified milk used in this study was a gift from Meiji Co. Ltd. (Tokyo, Japan). Part of this study was presented at a local meeting of the Japanese Society of Physical Fitness and Sports Medicine during March 2014 in Tokyo, Japan.
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Suzuki, Y., Maruyama-Nagao, A., Sakuraba, K. et al. Milk fortified with vitamin D could reduce the prevalence of vitamin D deficiency among Japanese female college students. Arch Osteoporos 9, 188 (2014). https://doi.org/10.1007/s11657-014-0188-x
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DOI: https://doi.org/10.1007/s11657-014-0188-x