Journal of General Internal Medicine

, Volume 29, Issue 8, pp 1139–1147

Associations Between Antidepressant Adherence and Shared Decision-Making, Patient–Provider Trust, and Communication Among Adults with Diabetes: Diabetes Study of Northern California (DISTANCE)

  • Amy M. Bauer
  • Melissa M. Parker
  • Dean Schillinger
  • Wayne Katon
  • Nancy Adler
  • Alyce S. Adams
  • Howard H. Moffet
  • Andrew J. Karter
Original Research

DOI: 10.1007/s11606-014-2845-6

Cite this article as:
Bauer, A.M., Parker, M.M., Schillinger, D. et al. J GEN INTERN MED (2014) 29: 1139. doi:10.1007/s11606-014-2845-6

ABSTRACT

BACKGROUND

Depression and adherence to antidepressant treatment are important clinical concerns in diabetes care. While patient–provider communication patterns have been associated with adherence for cardiometabolic medications, it is unknown whether interpersonal aspects of care impact antidepressant medication adherence.

OBJECTIVE

To determine whether shared decision-making, patient–provider trust, or communication are associated with early stage and ongoing antidepressant adherence.

DESIGN

Observational new prescription cohort study.

SETTING

Kaiser Permanente Northern California.

PATIENTS

One thousand five hundred twenty-three adults with type 2 diabetes who completed a survey in 2006 and received a new antidepressant prescription during 2006–2010.

MEASUREMENTS

Exposures included items based on the Trust in Physicians and Interpersonal Processes of Care instruments and the Consumer Assessment of Healthcare Providers and Systems (CAHPS) communication scale. Measures of adherence were estimated using validated methods with physician prescribing and pharmacy dispensing data: primary non-adherence (medication never dispensed), early non-persistence (dispensed once, never refilled), and new prescription medication gap (NPMG; proportion of time without medication during 12 months after initial prescription).

RESULTS

After adjusting for potential confounders, patients’ perceived lack of shared decision-making was significantly associated with primary non-adherence (RR = 2.42, p < 0.05), early non-persistence (RR = 1.34, p < 0.01) and NPMG (estimated 5 % greater gap in medication supply, p < 0.01). Less trust in provider was significantly associated with early non-persistence (RRs 1.22–1.25, ps < 0.05) and NPMG (estimated NPMG differences 5–8 %, ps < 0.01).

LIMITATIONS

All patients were insured and had consistent access to and quality of care.

CONCLUSIONS

Patients’ perceptions of their relationships with providers, including lack of shared decision-making or trust, demonstrated strong associations with antidepressant non-adherence. Further research should explore whether interventions for healthcare providers and systems that foster shared decision-making and trust might also improve medication adherence.

KEY WORDS

medication adherenceantidepressive agentsshared decision makingtrustphysician–patient relationsdiabetes mellitus

Copyright information

© Society of General Internal Medicine 2014

Authors and Affiliations

  • Amy M. Bauer
    • 1
  • Melissa M. Parker
    • 4
  • Dean Schillinger
    • 2
    • 3
  • Wayne Katon
    • 1
  • Nancy Adler
    • 5
  • Alyce S. Adams
    • 4
  • Howard H. Moffet
    • 4
  • Andrew J. Karter
    • 4
  1. 1.Department of Psychiatry and Behavioral SciencesUniversity of Washington School of MedicineSeattleUSA
  2. 2.Division of General Internal MedicineUniversity of CaliforniaSan FranciscoUSA
  3. 3.Center for Vulnerable PopulationsSan Francisco General Hospital and Trauma CenterSan FranciscoUSA
  4. 4.Division of Research, Kaiser Permanente Northern CaliforniaOaklandUSA
  5. 5.Departments of Psychiatry and Pediatrics and Center for Health and CommunityUniversity of CaliforniaSan FranciscoUSA