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Feasibility and Safety of Urgent Laparoscopic Cholecystectomy for Acute Cholecystitis After 4 Days from Symptom Onset

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Journal of Gastrointestinal Surgery Aims and scope

Abstract

Background

It is preferable to perform laparoscopic cholecystectomy for acute cholecystitis in the acute phase, within 72 h of symptom onset. The feasibility and safety of performing urgent laparoscopic cholecystectomy in the late phase (4–7 days after symptom onset) are unclear. The aim of this study was to clarify the feasibility and safety of late phase urgent laparoscopic cholecystectomy.

Methods

Between 2005 and 2014, 233 patients underwent urgent laparoscopic cholecystectomy for acute cholecystitis within 7 days. We compared clinical features and perioperative outcomes between patients who underwent laparoscopic cholecystectomy within 3 days (early phase group) and 4–7 days after symptom onset (late phase group).

Results

There were 193 patients in the early phase group and 40 patients in the late-phase group. Performing laparoscopic cholecystectomy in the late phase did not influence operation time, postoperative complications, or postoperative hospital stay. The rate of conversion to open surgery and blood loss were slightly higher in the late-phase group (8 % and 140 ml) compared with the early phase group (3 % and 69 ml) but were still acceptable.

Conclusions

Late phase urgent laparoscopic cholecystectomy for acute cholecystitis was feasible and safe.

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References

  1. Lahtinen J, Alhava EM, Aukee S: Acute cholecystitis treated by early and delayed surgery. A controlled clinical trial. Scand J Gastroenterol 1978;13:673–678.

    Article  CAS  PubMed  Google Scholar 

  2. Jarvinen HJ, Hastbacka J: Early cholecystectomy for acute cholecystitis: A prospective randomized study. Ann Surg 1980;191:501–505.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  3. Van der Linden W, Edlund G: Early versus delayed cholecystectomy: The effect of a change in management. Br J Surg 1981;68:753–757.

    Article  PubMed  Google Scholar 

  4. Norrby S, Herlin P, Holmin T, Sjodahl R, Tagesson C: Early or delayed cholecystectomy in acute cholecystitis? A clinical trial. Br J Surg 1983;70:163–165.

    Article  CAS  PubMed  Google Scholar 

  5. Yamashita Y, Takada T, Hirata K: A survey of the timing and approach to the surgical management of patients with acute cholecystitis in Japanese hospitals. J Hepatobiliary Pancreat Surg 2006;13:409–415.

    Article  PubMed  Google Scholar 

  6. Lo CM, Liu CL, Fan ST, Lai EC, Wong J: Prospective randomized study of early versus delayed laparoscopic cholecystectomy for acute cholecystitis. Ann Surg 1998;227:461–467.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  7. Lai PB, Kwong KH, Leung KL, Kwok SP, Chan AC, Chung SC, Lau WY: Randomized trial of early versus delayed laparoscopic cholecystectomy for acute cholecystitis. Br J Surg 1998;85:764–767.

    Article  CAS  PubMed  Google Scholar 

  8. Chandler CF, Lane JS, Ferguson P, Thompson JE, Ashley SW: Prospective evaluation of early versus delayed laparoscopic cholecystectomy for treatment of acute cholecystitis. Am Surg 2000;66:896–900.

    CAS  PubMed  Google Scholar 

  9. Lau H, Lo CY, Patil NG, Yuen WK: Early versus delayed-interval laparoscopic cholecystectomy for acute cholecystitis: A metaanalysis. Surg Endosc 2006;20:82–87.

    Article  CAS  PubMed  Google Scholar 

  10. Shikata S, Noguchi Y, Fukui T: Early versus delayed cholecystectomy for acute cholecystitis: A meta-analysis of randomized controlled trials. Surg Today 2005;35:553–560.

    Article  PubMed  Google Scholar 

  11. Siddiqui T, MacDonald A, Chong PS, Jenkins JT: Early versus delayed laparoscopic cholecystectomy for acute cholecystitis: A meta-analysis of randomized clinical trials. Am J Surg 2008;195:40–47.

    Article  PubMed  Google Scholar 

  12. Gurusamy K, Samraj K, Gluud C, Wilson E, Davidson BR: Meta-analysis of randomized controlled trials on the safety and effectiveness of early versus delayed laparoscopic cholecystectomy for acute cholecystitis. Br J Surg 2010;97:141–150.

    Article  CAS  PubMed  Google Scholar 

  13. Lo CM, Liu CL, Lai EC, Fan ST, Wong J: Early versus delayed laparoscopic cholecystectomy for treatment of acute cholecystitis. Ann Surg 1996;223:37–42.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  14. Madan AK, Aliabadi-Wahle S, Tesi D, Flint LM, Steinberg SM: How early is early laparoscopic treatment of acute cholecystitis? Am J Surg 2002;183:232–236.

    Article  PubMed  Google Scholar 

  15. Yamashita Y, Takada T, Kawarada Y, Nimura Y, Hirota M, Miura F, Mayumi T, Yoshida M, Strasberg S, Pitt HA, de Santibanes E, Belghiti J, Buchler MW, Gouma DJ, Fan ST, Hilvano SC, Lau JW, Kim SW, Belli G, Windsor JA, Liau KH, Sachakul V: Surgical treatment of patients with acute cholecystitis: Tokyo guidelines. J Hepatobiliary Pancreat Surg 2007;14:91–97.

    Article  PubMed Central  PubMed  Google Scholar 

  16. Yamashita Y, Takada T, Strasberg SM, Pitt HA, Gouma DJ, Garden OJ, Buchler MW, Gomi H, Dervenis C, Windsor JA, Kim SW, de Santibanes E, Padbury R, Chen XP, Chan AC, Fan ST, Jagannath P, Mayumi T, Yoshida M, Miura F, Tsuyuguchi T, Itoi T, Supe AN: Tg13 surgical management of acute cholecystitis. J Hepatobiliary Pancreat Sci 2013;20:89–96.

    Article  PubMed  Google Scholar 

  17. Yokoe M, Takada T, Strasberg SM, Solomkin JS, Mayumi T, Gomi H, Pitt HA, Garden OJ, Kiriyama S, Hata J, Gabata T, Yoshida M, Miura F, Okamoto K, Tsuyuguchi T, Itoi T, Yamashita Y, Dervenis C, Chan AC, Lau WY, Supe AN, Belli G, Hilvano SC, Liau KH, Kim MH, Kim SW, Ker CG: Tg13 diagnostic criteria and severity grading of acute cholecystitis (with videos). J Hepatobiliary Pancreat Sci 2013;20:35–46.

    Article  PubMed  Google Scholar 

  18. Noda T, Hatano H, Dono K, Shimizu J, Oshima K, Tanida T, Miyake M, Komori T, Kawanishi K, Morita S, Imamura H, Iwazawa T, Akagi K, Kitada M: Safety of early laparoscopic cholecystectomy for patients with acute cholecystitis undergoing antiplatelet or anticoagulation therapy: A single-institution experience. Hepatogastroenterology 2014;61:1501–1506.

    PubMed  Google Scholar 

  19. Strasberg SM, Hertl M, Soper NJ: An analysis of the problem of biliary injury during laparoscopic cholecystectomy. J Am Coll Surg 1995;180:101–125.

    CAS  PubMed  Google Scholar 

  20. Low JK, Barrow P, Owera A, Ammori BJ: Timing of laparoscopic cholecystectomy for acute cholecystitis: Evidence to support a proposal for an early interval surgery. Am Surg 2007;73:1188–1192.

    PubMed  Google Scholar 

  21. Ohta M, Iwashita Y, Yada K, Ogawa T, Kai S, Ishio T, Shibata K, Matsumoto T, Bandoh T, Kitano S: Operative timing of laparoscopic cholecystectomy for acute cholecystitis in a Japanese institute. Jsls 2012;16:65–70.

    Article  PubMed Central  PubMed  Google Scholar 

  22. Popkharitov AI: Laparoscopic cholecystectomy for acute cholecystitis. Langenbecks Arch Surg 2008;393:935–941.

    Article  PubMed  Google Scholar 

  23. Gutt CN, Encke J, Koninger J, Harnoss JC, Weigand K, Kipfmuller K, Schunter O, Gotze T, Golling MT, Menges M, Klar E, Feilhauer K, Zoller WG, Ridwelski K, Ackmann S, Baron A, Schon MR, Seitz HK, Daniel D, Stremmel W, Buchler MW: Acute cholecystitis: Early versus delayed cholecystectomy, a multicenter randomized trial (ACDC study, NCT00447304). Ann Surg 2013;258:385–393.

    Article  PubMed  Google Scholar 

  24. Peng WK, Sheikh Z, Nixon SJ, Paterson-Brown S: Role of laparoscopic cholecystectomy in the early management of acute gallbladder disease. Br J Surg 2005;92:586–591.

    Article  CAS  PubMed  Google Scholar 

  25. Choi SB, Han HJ, Kim CY, Kim WB, Song TJ, Suh SO, Kim YC, Choi SY: Early laparoscopic cholecystectomy is the appropriate management for acute gangrenous cholecystitis. Am Surg 2011;77:401–406.

    PubMed  Google Scholar 

  26. Wu JX, Nguyen AT, de Virgilio C, Plurad DS, Kaji AH, Nguyen V, Gifford E, de Virgilio M, Ayabe R, Saltzman D, Kim D: Can it wait until morning? A comparison of nighttime versus daytime cholecystectomy for acute cholecystitis. Am J Surg 2014;208:911–918; discussion 917–918.

    Article  PubMed  Google Scholar 

  27. Johansson M, Thune A, Blomqvist A, Nelvin L, Lundell L: Management of acute cholecystitis in the laparoscopic era: Results of a prospective, randomized clinical trial. J Gastrointest Surg 2003;7:642–645.

    Article  PubMed  Google Scholar 

  28. Singer JA, McKeen RV: Laparoscopic cholecystectomy for acute or gangrenous cholecystitis. Am Surg 1994;60:326–328.

    CAS  PubMed  Google Scholar 

  29. Eldar S, Sabo E, Nash E, Abrahamson J, Matter I: Laparoscopic cholecystectomy for the various types of gallbladder inflammation: A prospective trial. Surg Laparosc Endosc 1998;8:200–207.

    Article  CAS  PubMed  Google Scholar 

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Disclosures

None of the authors have any conflicts of interest or financial ties to disclose.

Author Contributions

Study design: T. Noda and K. Dono

Acquisition of data: G. Shinke, T. Noda, and H. Hatano

Analysis and interpretation: T. Noda, K. Dono, and J. Shimizu

Manuscript drafted by G. Shinke and T. Noda

Revision: M. Hirota, A. Takata, K. Oshima, T. Tanida, T. Komori, S. Morita, H. Imamura

Statistical advice: T. Iwazawa and K. Akagi

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Correspondence to Takehiro Noda.

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Shinke, G., Noda, T., Hatano, H. et al. Feasibility and Safety of Urgent Laparoscopic Cholecystectomy for Acute Cholecystitis After 4 Days from Symptom Onset. J Gastrointest Surg 19, 1787–1793 (2015). https://doi.org/10.1007/s11605-015-2878-0

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  • DOI: https://doi.org/10.1007/s11605-015-2878-0

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