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False-Positive PET/CT After Cyanoacrylate Sealing of a Pancreaticojejunostomy

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Abstract

In 2013, a 68-year-old male had a pancreaticoduodenectomy for pancreatic cancer. The pancreaticojejunostomy was sealed with cyanoacrylate (Dermabond) to prevent postoperative pancreatic fistula. Local recurrence of malignancy at the anastomosis was suspected 18 months later in PET/CT. Surgical revision was performed and anastomosis resected. However, histology showed no tumor recurrence, but strong inflammation and foreign-body reaction towards Dermabond. The sealant caused false-positive PET/CT findings, so its use in oncologic surgery should be abandoned.

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Authors’ contributions

OB contributed to the acquisition of the data, draft of the manuscript, and final approval. JM contributed to the acquisition and interpretation of the data, critical revision, and final approval. AT contributed to the interpretation of data, critical revision, and final approval. WU contributed to the acquisition and interpretation of data, critical revision, and final approval.

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Authors and Affiliations

  1. Department of Surgery, St. Josef Hospital, Ruhr University of Bochum, Gudrunstr. 56, 44791, Bochum, Germany

    Orlin Belyaev & Waldemar Uhl

  2. Institute of Pathology, Ruhr University of Bochum, Bochum, Germany

    Johanna Munding & Andrea Tannapfel

Authors
  1. Orlin Belyaev
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  2. Johanna Munding
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  3. Andrea Tannapfel
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  4. Waldemar Uhl
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Correspondence to Orlin Belyaev.

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Belyaev, O., Munding, J., Tannapfel, A. et al. False-Positive PET/CT After Cyanoacrylate Sealing of a Pancreaticojejunostomy. J Gastrointest Surg 19, 984–985 (2015). https://doi.org/10.1007/s11605-015-2780-9

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  • DOI: https://doi.org/10.1007/s11605-015-2780-9

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