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Coronary computed tomography angiography using 128-slice dual-source computed tomography in patients with severe calcification

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Japanese Journal of Radiology Aims and scope Submit manuscript

Abstract

Purpose

To compare coronary computed tomography angiography (CTA) and coronary angiography (CAG) with regard to luminal graphic definition of calcified segments using 128-slice dual-source computed tomography (DSCT), specifically for patients with an Agatston score >400.

Materials and methods

Of 1148 consecutive patients who underwent coronary CTA using a 128-slice DSCT, 132 subjects had severe calcification with an Agatston score >400. Thirty-nine of the 132 patients who had undergone CAG within 3 months before or after coronary CTA were included. We investigated the distribution of calcification, and we visually evaluated significant stenosis in the calcified and all segments. Results were compared with CAG.

Results

The target group in this study had a very high mean Agatston score of 1771 ± 1724. Results for sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of 247 calcified vs all 325 segments were as follows: sensitivity 93.2 vs 92.2%, specificity 83.9 vs 87.5%, PPV 70.8 vs 69.6%, and NPV 96.7 vs 97.3%, respectively.

Conclusion

128-slice DSCT has potential for evaluation of calcified segments in the lumen, even in patients whose Agatston score exceeds 400.

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Abbreviations

BMI:

Body mass index

CTDIvol:

Volume CT dose index

DLP:

Dose length product

CTA:

Computed tomography angiography

CAG:

Coronary angiography

PPV:

Positive predictive value

NPV:

Negative predictive value

MDCT:

Multidetector row CT

DSCT:

Dual source CT

RCA:

Right coronary artery

LAD:

Left anterior descending

LCx:

Left circumflex

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Authors and Affiliations

  1. Department of Radiology and Radiation Oncology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuo-ku, Niigata-City, Niigata, 951-8510, Japan

    Suguru Sato, Yosuke Horii, Norihiko Yoshimura, Takuya Yagi & Hidefumi Aoyama

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  1. Suguru Sato
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  2. Yosuke Horii
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  3. Norihiko Yoshimura
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  4. Takuya Yagi
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  5. Hidefumi Aoyama
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Correspondence to Norihiko Yoshimura.

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Sato, S., Horii, Y., Yoshimura, N. et al. Coronary computed tomography angiography using 128-slice dual-source computed tomography in patients with severe calcification. Jpn J Radiol 35, 432–439 (2017). https://doi.org/10.1007/s11604-017-0650-y

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  • DOI: https://doi.org/10.1007/s11604-017-0650-y

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